CCR8 Antibody

Images

 
Immunohistochemistry-Paraffin: CCR8 Antibody [NB100-709] - Section of mouse spleen.

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, ELISA, IHC, IHC-P
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

CCR8 Antibody Summary

Immunogen
Synthetic peptide: PNVTMTDYYPDFFTAPCDAEFLLRGSM, corresponding to amino acids 7-33 of Mouse CCR8.
Localization
Cell Membrane
Specificity
This recognizes CCR8 (50 kDa). The peptide sequence is < 50 % identical to other mouse chemokine receptors in this region.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
CCR8
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:50000
  • Immunohistochemistry 1:200
  • Immunohistochemistry-Paraffin 1:200
  • Western Blot 1:500
Control
Mouse Spleen Whole Tissue Lysate (Adult Whole Normal)
Publications
Read Publications using NB100-709.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
10mM KHPO4 and 0.14M NaCl, BSA
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CCR8 Antibody

  • CC chemokine receptor 8
  • C-C CKR-8
  • CC-chemokine receptor chemr1
  • CC-CKR-8
  • CCR8
  • CCR-8
  • CD198
  • CDw198 antigen
  • CDw198
  • chemokine (C-C motif) receptor 8
  • chemokine (C-C) receptor 8
  • chemokine (C-C) receptor-like 2
  • Chemokine receptor-like 1
  • ChemR1
  • CKRL1
  • CKR-L1
  • CKRL1MGC129966
  • CMKBR8MGC129973
  • CMKBRL2C-C chemokine receptor type 8
  • CY6
  • GPRCL1
  • GPRCY6
  • GPR-CY6
  • TER-1
  • TER1CC chemokine receptor CHEMR1

Background

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation regulated cytokine (TARC) and macrophage inflammatory protein 1 beta (MIP1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. CCR8 expression has been reported in spleen and thymus, natural killer cells, monocytes, and T cells, and at lower levels in peripheral blood leukocytes. CCR* is also believed to be alternative coreceptor with CD4 for HIV-1 infection.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

DY272
Species: Hu
Applications: ELISA
MAB182
Species: Hu
Applications: CyTOF-ready, Flow, ICC, Neut
MAB1567
Species: Hu
Applications: CyTOF-reported, Flow
NBP2-37856
Species: Hu
Applications: ICC/IF, IHC, IHC-P
NBP1-86564
Species: Hu
Applications: ICC/IF, IHC, IHC-P
MAB155
Species: Hu
Applications: CyTOF-ready, Flow, IHC, Neut
MCC170
Species: Mu
Applications: ELISA
MAB172
Species: Hu
Applications: CyTOF-ready, Flow, IHC, Neut
DMD00
Species: Hu
Applications: ELISA
MAB145
Species: Hu
Applications: CyTOF-ready, Flow
NBP1-19371
Species: Ca, Hu, Mu, Po, Rb, Rt
Applications: Dual ISH-IHC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, Simple Western, WB
MAB160
Species: Hu
Applications: CyTOF-ready, Flow, IHC, Neut
NBP2-35334
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, WB
DCP00
Species: Hu
Applications: ELISA
DRN00B
Species: Hu
Applications: ELISA
6507-IL/CF
Species: Hu
Applications: BA
MAB5519
Species: Mu
Applications: CyTOF-ready, Flow, ICC
MAB197
Species: Hu
Applications: CyTOF-reported, Flow, ICC, IHC, Neut
MAB195
Species: Hu
Applications: CyTOF-ready, Flow, IHC
285-IF
Species: Hu
Applications: BA

Publications for CCR8 Antibody (NB100-709)(2)

Reviews for CCR8 Antibody (NB100-709) (0)

There are no reviews for CCR8 Antibody (NB100-709). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for CCR8 Antibody (NB100-709) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Additional CCR8 Products

Bioinformatics Tool for CCR8 Antibody (NB100-709)

Discover related pathways, diseases and genes to CCR8 Antibody (NB100-709). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for CCR8 Antibody (NB100-709)

Discover more about diseases related to CCR8 Antibody (NB100-709).
 

Pathways for CCR8 Antibody (NB100-709)

View related products by pathway.

PTMs for CCR8 Antibody (NB100-709)

Learn more about PTMs related to CCR8 Antibody (NB100-709).
 

Research Areas for CCR8 Antibody (NB100-709)

Find related products by research area.

Blogs on CCR8

There are no specific blogs for CCR8, but you can read our latest blog posts.
Download our IHC Handbook

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our CCR8 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol CCR8
Entrez
Uniprot