CCR3 Antibody (5E8) - BSA Free

Flow Cytometry: CCR3 Antibody (5E8) [NBP3-09149] - Analysis (surface staining) of CD193 in human peripheral blood with anti-human CD193 (5E8) purified, GAM-APC.

• Reactivity: Hu
• Applications: Flow
• Clone: 5E8
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

CCR3 Antibody (5E8) - BSA Free Summary

• Immunogen: Tissue / cell preparation (Human) - human CCR3 transfected into mouse B cell lymphoma L1.2 cells.
• Specificity: The mouse monoclonal antibody 5E8 recognizes an extracellular epitope of CD193 (chemokine receptor 3), an approximately 41 kDa protein expressed above all in eosinophils and basophils.
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CCR3
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1-4 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for CCR3 Antibody (5E8) - BSA Free

• b-chemokine receptor
• CC chemokine receptor 3
• C-C chemokine receptor type 3
• C-C CKR-3
• CCR3
• CCR-3
• CD193 antigen
• CD193
• chemokine (C-C motif) receptor 3
• CKR3CC-CKR-3CMKBR3CD193
• eosinophil CC chemokine receptor 3
• Eosinophil eotaxin receptor
• MGC102841

Background

CKR3, or C-C chemokine receptor type 3, is a G protein-coupled, seven-transmembrane domain receptor protein. The chemokine eotaxin appears to be a highly specific agonist for CKR3, making CKR3 one of the factors responsible for selective recruitment of eosinophils to sites of inflammation (1). It has been shown that more than one chemokine activates CKR3, including eotaxin, RANTES, and MCP-3 (2). Since CKR3 is prominently expressed in eosinophils , it has been named the human eosinophil eotaxin receptor (2,3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CCR3