CCR11 Antibody

Immunohistochemistry-Paraffin: CCR11 Antibody [NB100-705] - Immunohistochemistry with antibody to human CCR11 on paraffin section of human lung.

Immunohistochemistry-Paraffin: CCR11 Antibody [NB100-705] - paraffin section mouse lung

Product Discontinued

CCR11 Antibody Summary

• Immunogen: Synthetic peptide: EQNQSTDYYYEENEMNGTYDYSQYELIC, corresponding to amino acids 4-31 of Human CCR11.
• Specificity: Peptide sequence is < 50 % identical to other human chemokine receptors in this region.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ACKR4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:37500
  • Immunohistochemistry 1:125
  • Immunohistochemistry-Paraffin 1:125
  • Western Blot 1:500
• Control:

  Human Small Intestine Whole Tissue Lysate (Adult Whole Normal)
  Human Heart Whole Tissue Lysate (Adult Whole Normal)

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: 10mM KHPO4, 0.14M NaCl and 1.0 mg/ml BSA
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for CCR11 Antibody

• ACKR4
• CC chemokine receptor-like 1
• C-C CKR-11
• CCBP2CCX CKR
• CC-CKR-11
• CCR11
• CCR11CCR10
• CCRL1
• CCX-CKR
• chemokine (C-C motif) receptor-like 1
• orphan seven-transmembrane receptor, chemokine related
• PPR1
• PPR1cc motif, receptor-like protein 1
• VSHK1
• VSHK1CKR-11

Background

Receptors for the C-C chemokine family include CCR-1, CCR-2A, CCR-3, CCR-4, CCR-5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. CCR11 in particular is expressed in the heart, lung, and small intestine. It binds members of the monocyte chemoattractant family including MCP-1, MCP-2, and MCP-4.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ACKR4
• Entrez:
  • 51554(Human)
  • 252837(Mouse)