Recombinant Mouse CCL20/MIP-3 alpha Protein

Images

 
SDS-Page: Mouse CCL20/MIP-3 alpha Protein [NBP2-35091]

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Func, PAGE
Format
Carrier-Free
Concentration
LYOPH

Order Details

View Available Formulations
Catalog# & Formulation Size Price

Recombinant Mouse CCL20/MIP-3 alpha Protein Summary

Description
A single, non-glycosylated biologically active polypeptide chain corresponding to 70 residues of CCL20.

Source: E. coli

Amino Acid Sequence: ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM

Preparation
Method
Novus' biologically active proteins are stringently purified to provide only the safest and most highly effective proteins available. This protein was expressed in E. coli, purified by HPLC, QC tested by SDS-PAGE and Western Blot and validated on appropriate cell lines for bioactivity. All HPLC and bioactivity data is provided for your assurance.
Details of Functionality
Macrophage Inflammatory Protein 3 alpha Protein is fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human CCR6 transfected murine BaF3 cells is in a concentration range of 0.1-10 ng/m
Source
E. coli
Protein/Peptide Type
Biologically Active Protein
Gene
CCL20
Purity
>96%, by HPLC
Endotoxin Note
Less than 1 EU/ug of endotoxin as determined by LAL method

Applications/Dilutions

Theoretical MW
8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.
Buffer
Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
Concentration
LYOPH
Purity
>96%, by HPLC
Reconstitution Instructions
Reconstitute with sterilized distilled water or 0.1% BSA aqueous buffer to a final concentration of 0.1 - 1.0 mg/ml.

Notes

This lyophilized preparation is stable at 2-8 degrees C, but should be kept at -20 degrees C for long term storage, preferably desiccated. Upon reconstitution, the preparation is most stable at -20 to -80 degrees C, and can be stored for one week at 2-8 degrees C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degrees C to -80 degrees C. Avoid repeated freeze/thaw cycles.

Alternate Names for Recombinant Mouse CCL20/MIP-3 alpha Protein

  • beta chemokine exodus-1
  • Beta-chemokine exodus-1
  • CC chemokine LARC
  • C-C motif chemokine 20
  • CCL20
  • chemokine (C-C motif) ligand 20
  • CKb4
  • exodus-1
  • LARC
  • LARCLiver and activation-regulated chemokine
  • MIP3 alpha
  • MIP-3 alpha
  • MIP-3 alpha/CCL20
  • MIP-3
  • MIP-3a
  • MIP-3-alpha
  • MIP3AMacrophage inflammatory protein 3 alpha
  • SCYA20Small-inducible cytokine A20
  • small inducible cytokine subfamily A (Cys-Cys), member 20
  • ST38

Background

CCL20, also named LARC (Liver and Activation-regulated Chemokine), is encoded by CCL20 located on chromosome 1 in mouse. The expression can be induced by LPS and some inflammatory cytokines, and it is at a high level in lymph nodes, PBL, fatal liver, fatal lung, appendix and so on. CCL20 has functions of chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. CCL20 elicits it effects by binding with CCR6 receptor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 2 years from date of receipt.

Customers Who Viewed This Item Also Viewed...

MAB195
Species: Hu
Applications: Flow, IHC, CyTOF-ready
MAB5519
Species: Mu
Applications: Flow, CyTOF-ready, ICC
MAB208
Species: Hu
Applications: WB, CyTOF-ready, ELISA(Cap), ELISA(Det), ICC, ICFlow, Neut, ELISA(Sta)
NBP1-92684
Species: Hu, Mu, Rt, Po, Bv
Applications: WB, ICC/IF
NBP1-19371
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
MAB197
Species: Hu
Applications: Flow, CyTOF-reported, ICC, Neut
NBP2-29323
Species: Hu, Mu, Rt, Bv, Ca, Ch, Xp
NBP2-35091
Species: Mu
Applications: Func, PAGE

Publications for CCL20/MIP-3 alpha Protein (NBP2-35091) (0)

There are no publications for CCL20/MIP-3 alpha Protein (NBP2-35091).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for CCL20/MIP-3 alpha Protein (NBP2-35091) (0)

There are no reviews for CCL20/MIP-3 alpha Protein (NBP2-35091). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

FAQs for CCL20/MIP-3 alpha Protein (NBP2-35091) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional CCL20/MIP-3 alpha Products

Bioinformatics Tool for CCL20/MIP-3 alpha Protein (NBP2-35091)

Discover related pathways, diseases and genes to CCL20/MIP-3 alpha Protein (NBP2-35091). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for CCL20/MIP-3 alpha Protein (NBP2-35091)

Discover more about diseases related to CCL20/MIP-3 alpha Protein (NBP2-35091).
 

Pathways for CCL20/MIP-3 alpha Protein (NBP2-35091)

View related products by pathway.

PTMs for CCL20/MIP-3 alpha Protein (NBP2-35091)

Learn more about PTMs related to CCL20/MIP-3 alpha Protein (NBP2-35091).
 

Research Areas for CCL20/MIP-3 alpha Protein (NBP2-35091)

Find related products by research area.

Blogs on CCL20/MIP-3 alpha

There are no specific blogs for CCL20/MIP-3 alpha, but you can read our latest blog posts.

Customers Who Bought This Also Bought

IL-4 [Unconjugated]
204-IL-010/CF

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Recombinant Mouse CCL20/MIP-3 alpha Protein and receive a gift card or discount.

Bioinformatics

Gene Symbol CCL20
Entrez
Uniprot