Mouse CXCL1/KC DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Mouse CXCL1/KC DuoSet ELISA, 15 Plate Summary

Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Cxcl1

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY453.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse CXCL1/KC DuoSet ELISA, 15 Plate

  • CINC1
  • CINC-1
  • CXCL1
  • FSP
  • GRO alpha
  • GRO1
  • GROa
  • KC
  • MGSA
  • MGSA-a
  • MGSA-alpha
  • NAP-3
  • SCYB1

Background

CXCL1/GRO alpha, also known as KC in mouse and CINC-1 in rat, is a member of the CXC family of chemokines. Human CXCL1/GRO alpha is 107 amino acids (aa) in length with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 57% and 59% amino acid sequence identity with the human protein, respectively. Genome-wide analysis suggests that the protein encoded by the mouse Cxcl3 gene is homologous to human CXCL1/GRO alpha protein. Human CXCL1/GRO alpha can be cleaved into three isoforms CXCL1/GRO alpha (aa 4-73), CXCL1/GRO alpha (aa 5-73), and CXCL1/GRO alpha (aa 6-73) which show higher activity than the full length protein. CXCL1/GRO alpha is secreted by mast cells and macrophages whereupon it acts as a chemoattractant for neutrophils.

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Publications for CXCL1/GRO alpha/KC/CINC-1 (DY453)(311)

We have publications tested in 3 confirmed species: Human, Mouse, Transgenic Mouse.


Filter By Application
All Applications
Filter By Species
Human
(3)
Mouse
(307)
Transgenic Mouse
(12)
All Species
Showing Publications 1 - 10 of 311. Show All 311 Publications.
Publications using DY453 Applications Species
Tindal, EW;Chung, CS;Chen, Y;Zhu, R;Ayala, A; Differential Effects of Endothelial Cell- as opposed to Neutrophil-Lineage Restricted PD-L1 Gene Expression on Experimental Murine Shock/ Sepsis-Induced Lung Injury Research square 2025-10-07 [PMID: 41282243] (Mouse) Mouse
Yang, J;Xu, B;Cao, J;Liu, Y;Tang, L;Zhao, P;Li, S;Li, X;Liu, J;Yu, R;Tang, Y;Tan, W;Ding, H;Li, J;Liu, Y; Characterizing the mechanisms underpinning interleukin-15R?-mediated protection against sepsis and candidiasis Cytokine 2025-09-17 [PMID: 40967153] (Mouse, Transgenic Mouse) Mouse, Transgenic Mouse
Tanino, Y;Wang, X;Nikaido, T;Sato, Y;Togawa, R;Watanabe, N;Tanino, M;Kadomatsu, K;Shibata, Y; Midkine Deficiency Attenuates Lipopolysaccharide-Induced Pulmonary Inflammation International journal of molecular sciences 2025-09-02 [PMID: 40943439] (Mouse, Transgenic Mouse) Mouse, Transgenic Mouse
Brune, JE;Chang, MY;Tang, F;Lopez-Martinez, C;Reeves, SR;Chan, CK;Waldron, P;Boyd, DF;Gharib, SA;Thomas, PG;Altemeier, WA;Frevert, CW; Immunomodulation of the Innate Host Response by Mesenchymal-Derived Versican during Influenza A Virus Infection bioRxiv : the preprint server for biology 2025-08-02 [PMID: 40766376] (Mouse) Mouse
Molczyk, C;Sturgeon, R;Saxena, S;Johnsson, E;Bhatia, R;Bhyrabhatla, N;Kumar, S;Batra, SK;Singh, RK; Unlocking the Power of CXCR2 Inhibition to Overcome Gemcitabine Resistance in Pancreatic Cancer bioRxiv : the preprint server for biology 2025-06-28 [PMID: 40667309] (Mouse) Mouse
Kumar, A;O'Brien, M;Young, VB;Yung, R; Single-cell RNA sequencing identifies accumulation of Fcgr2b+ virtual memory like CD8 T cells with cytotoxic and inflammatory potential in aged mouse white adipose tissue bioRxiv : the preprint server for biology 2025-06-30 [PMID: 40631318] (Mouse) Mouse
Zeydabadinejad, S;Kim, JSA;Zheng, A;Kandalgaonkar, MR;Ababio, PB;Vijay-Kumar, M;Yeoh, BS;Saha, P; Targeting anemia-induced CD71+ reticulocytes protects mice from Plasmodium infection Infection and Immunity 2025-07-01 [PMID: 40590713] (Mouse) Mouse
Woods, PS;Cetin-Atalay, R;Meliton, AY;Sun, KA;Shamaa, OR;Shin, KWD;Tian, Y;Haugen, B;Hamanaka, RB;Mutlu, GM; HIF-1 regulates mitochondrial function in bone marrow-derived macrophages but not in tissue-resident alveolar macrophages Scientific reports 2025-04-04 [PMID: 40185846] (Mouse) Mouse
Faizan, MI;Kaur, G;Shaikh, SB;Effah, F;Unwalla, H;Rahman, I; Genetic diversity leads to differential inflammatory responses to cigarette smoke in mice Physiological reports 2025-01-01 [PMID: 39844449] (Mouse) Mouse
Cook, PC;Brown, SL;Houlder, EL;Furlong-Silva, J;Conn, DP;Colombo, SAP;Baker, S;Svedberg, FR;Howell, G;Bertuzzi, M;Boon, L;Konkel, JE;Thornton, CR;Allen, JE;MacDonald, AS; Mgl2+ cDC2s coordinate fungal allergic airway type 2, but not type 17, inflammation in mice Nature communications 2025-01-22 [PMID: 39843887] (Mouse) Mouse
Show All 311 Publications.

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Product General Protocols

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FAQs for CXCL1/GRO alpha/KC/CINC-1 (DY453). (Showing 1 - 1 of 1 FAQs).

  1. What is the difference between the Quantikine and Duoset ELISA kits?
    • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

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Bioinformatics

Gene Symbol Cxcl1