CCL20/MIP-3 alpha Antibody

Immunohistochemistry-Paraffin: CCL20/MIP-3 alpha Antibody [NBP1-45246] - (6ug/ml) staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

• Reactivity: Hu, Po, Bv
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

CCL20/MIP-3 alpha Antibody Summary

• Immunogen: Peptide with sequence CLGYTDRILHPK corresponding to internal region according to NP_004582.1, NP_001123518.1.
• Specificity: This antibody is expected to recognize both isoforms (NP_004582.1; NP_001123518.1).
• Predicted Species: Porcine (100%), Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: CCL20
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 6 - 8 ug/ml
  • Immunohistochemistry-Paraffin 6 - 8 ug/ml
  • Peptide ELISA Detection limit 1:16000
• Application Notes: WB: Preliminary experiments in human peripheral blood mononucleocytes lysates gave no specific signal but low background. IHC-P: Human liver shows local staining between the hepatocytes.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for CCL20/MIP-3 alpha Antibody

• beta chemokine exodus-1
• Beta-chemokine exodus-1
• CC chemokine LARC
• C-C motif chemokine 20
• CCL20
• chemokine (C-C motif) ligand 20
• CKb4
• exodus-1
• LARC
• LARCLiver and activation-regulated chemokine
• MIP3 alpha
• MIP-3 alpha
• MIP-3a
• MIP-3-alpha
• MIP3AMacrophage inflammatory protein 3 alpha
• SCYA20Small-inducible cytokine A20
• small inducible cytokine subfamily A (Cys-Cys), member 20
• ST38

Background

Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibitsproliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of themucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processedforms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coliATCC 25922 and S.aureus ATCC 29213

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CCL20/MIP-3 alpha Antibody (NBP1-45246)(1)

Publication using NBP1-45246

• Punj V, Matta H, Schamus S et al. Induction of CCL20 production by Kaposi sarcoma-associated herpesvirus: role of viral FLICE inhibitory protein K13-induced NF-kappaB activation. Blood 2009-05-01 [PMID: 19324905]

Bioinformatics

• Gene Symbol: CCL20
• Entrez:
  • 6364(Human)
• Uniprot:
  • P78556()