Cathepsin G Native Protein

Product Discontinued

Cathepsin G Native Protein Summary

• Description: Native Cathepsin G
  
  Source:Human Neutrophil
  Amino Acid Sequence:(P08311)
  
  This product is manufactured by Abcam and distributed by Novus Biologicals. (Abcam Catalog Number: ab91122)
• Source: Human neutrophil
• Protein/Peptide Type: Native Protein
• Gene: CTSG
• Purity: >95%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • Bioactivity
  • SDS-Page
• Application Notes: Specific activity: 2 to 4 units per mg protein. One unit of activity is defined as the amount of enzyme that hydrolyzes one micromole of Suc-Ala-Ala-Pro-Phe-pNA (1 mM) per minute at 25C in 160 mM Tris-HCl, pH 7.4, with 1.6 M NaCl.
• Theoretical MW: 23.5 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
• Buffer: Salt-free lyophilized solid
• Concentration: Lyoph
• Purity: >95%, by SDS-PAGE
• Reconstitution Instructions: Reconstitute with deionized H2O.

Alternate Names for Cathepsin G Native Protein

• cathepsin G
• CathepsinG
• CGCATG
• EC 3.4.21
• EC 3.4.21.20
• MGC23078

Background

Cathepsin G is a serine protease secreted by activated neutrophils that play a role in the inflammatory response. This enzyme degrades collagen and proteoglycan and can also cause the release of angiotensin II from angiotensin I or angiotensinogen. It has been implicated in connective tissue diseases such as emphysema and rheumatoid arthritis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: CTSG