Caspase-4 Antibody


Western Blot: Caspase-4 Antibody [NBP1-77208] - Human spleen cells with caspase-4 antibody at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry: Caspase-4 Antibody [NBP1-77208] - Immunofluorescence of Caspase-4 in A20 cells with Caspase-4 antibody at 10 ug/mL.
Immunohistochemistry-Paraffin: Caspase-4 Antibody [NBP1-77208] - Human spleen tissue using caspase-4 antibody at 2 ug/ml.

Product Details

Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, IHC, IHC-P, ICC, IF
1 mg/ml

Order Details

Caspase-4 Antibody Summary

Antibody was raised against a 15 amino acid peptide from near the center of human Caspase-4.
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
1 mg/ml
Immunogen affinity purified


  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunocytochemistry 10 ug/ml
  • Immunofluorescence 10 ug/ml
Application Notes
Casp-4 antibody can be used for the detection of Caspase-4 by Western blot at 2 mg/ml. Depending on cell lines or tissues used, other cleavage products may be observed.
Control Peptide
Caspase-4 Peptide (NBP1-77208PEP)

Alternate Names for Caspase-4 Antibody

  • apoptotic cysteine protease Mih1/TX
  • CASP4
  • CASP-4
  • caspase 4, apoptosis-related cysteine peptidase
  • caspase 4, apoptosis-related cysteine protease
  • Caspase4
  • caspase-4
  • EC 3.4.22
  • EC
  • ICE(rel)II
  • ICE(rel)-II
  • ICH2
  • ICH-2
  • Mih1/TX
  • Protease ICH-2
  • Protease TX
  • TX


Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1beta and IL-18. Caspase-4 was initially identified as a homologous protein to Caspase-1 and the C. elegans Ced-3 which could induce apoptosis in transfected cells. More recent studies have shown that it can be activated by ER stress and has been suggested to be involved in multiple neuronal pathologies such as Alzheimer's disease.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB
Applications: WB
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt, Po, ChHa, Ma
Applications: WB, Simple Western, EM, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Species: Hu, Mu, Rt, Pm
Applications: WB, Simple Western, GS, ICC/IF, IHC, IHC-P, IP
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, IHC-P
Species: Hu, Mu, Rt, Ch, Sh
Applications: WB, Simple Western, Flow, ICC/IF
Species: Hu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt, Ge
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Species: Hu, Mu, Rt, Ca, Ge
Applications: IHC, IHC-Fr, IHC-P, IP, Flow-IC
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu
Applications: WB, ELISA, IHC, IHC-P, ICC, IF

Publications for Caspase-4 Antibody (NBP1-77208) (0)

There are no publications for Caspase-4 Antibody (NBP1-77208).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Caspase-4 Antibody (NBP1-77208) (0)

There are no reviews for Caspase-4 Antibody (NBP1-77208). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Caspase-4 Antibody (NBP1-77208) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies


Isotype Controls

Additional Caspase-4 Antibody Products

Related Products by Gene

Bioinformatics Tool for Caspase-4 Antibody (NBP1-77208)

Discover related pathways, diseases and genes to Caspase-4 Antibody (NBP1-77208). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Caspase-4 Antibody (NBP1-77208)

Discover more about diseases related to Caspase-4 Antibody (NBP1-77208).

Pathways for Caspase-4 Antibody (NBP1-77208)

View related products by pathway.

PTMs for Caspase-4 Antibody (NBP1-77208)

Learn more about PTMs related to Caspase-4 Antibody (NBP1-77208).

Research Areas for Caspase-4 Antibody (NBP1-77208)

Find related products by research area.

Blogs on Caspase-4.

Caspase-4 - a human protease with roles in inflammation and immunity
Caspases are a family of cysteine-aspartic acid proteases that cleave caspase proenzymes as well as other protein substrates. Caspases are well known for their role in apoptosis, but they also play a significant role in other cellular processes inc...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol CASP4

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on NBP1-77208 below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.

Customers Who Bought This Also Bought