Caspase-4 Products

Antibodies
Caspase-4 Antibody
Caspase-4 Antibody
NBP1-76602
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Caspase-4 Antibody
Caspase-4 Antibody
NBP1-77208
Species: Hu, Mu
Applications: WB, ELISA, IHC, IHC-P, ICC, IF
Host: Rabbit Polyclonal
Caspase-4 Antibody
Caspase-4 Antibody
NBP1-51267
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Kits
Caspase-4 Assay Kit
Caspase-4 Assay Kit
KA0747
Species: Ma
Applications: Func
Caspase-4 Assay Kit
Caspase-4 Assay Kit
KA0745
Species: Ma
Applications: Func
Caspase-4 Fluorometric Assay ...
Caspase-4 Fluorometric Assay Kit
KA0746
Species: Ma
Applications: Func
Lysates
Caspase-4 Overexpression Lysa ...
Caspase-4 Overexpression Lysate (N...
NBL1-08712
Applications: WB
Caspase-4 Overexpression Lysa ...
Caspase-4 Overexpression Lysate (N...
NBL1-08713
Applications: WB
Proteins
Caspase-4 Recombinant Protein ...
Caspase-4 Recombinant Protein
H00000837-P01
Species: Hu
Applications: WB, ELISA, PA
Caspase-4 Recombinant Protein ...
Caspase-4 Recombinant Protein Antigen
NBP1-87681PEP
Species: Hu
Applications: AC
Caspase-4 Peptide
Caspase-4 Peptide
NBP1-77208PEP
Species: Hu
Applications: AC

Description

Caspase 4 encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 837
Alternate Names
  • EC 3.4.22
  • CASP-4
  • ICH2
  • Protease TX
  • EC 3.4.22.57
  • Protease ICH-2
  • caspase-4
  • caspase 4, apoptosis-related cysteine protease
  • apoptotic cysteine protease Mih1/TX
  • TX
  • Mih1/TX
  • ICH-2
  • ICEREL-II
  • ICE(rel)II
  • ICE(rel)-II
  • caspase 4, apoptosis-related cysteine peptidase

Research Areas for Caspase-4

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Caspases

PTMs for Caspase-4

Learn more about PTMs related to Caspase-4.

Cleavage
Phosphorylation
Glycosylation
Dephosphorylation
Deglycosylation
Ubiquitination

Bioinformatics Tool for Caspase-4

Discover related pathways, diseases and genes to Caspase-4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Caspase-4 Blog Posts

Check out the latest blog posts on Caspase-4.
Caspase-4 - a human protease with roles in inflammation and immunity
Caspases are a family of cysteine-aspartic acid proteases that cleave caspase proenzymes as well as other protein substrates. Caspases are well known for their role in apoptosis, but they also play a significant role in other cellular processes inc...    Read more.
Read more Caspase-4 related blogs.