Alternate Names for Carbonic Anhydrase XII/CA12 Antibody (OTI2C6) [FITC]
CA12
Carbonate dehydratase XII
carbonic anhydrase 12
Carbonic Anhydrase XII
carbonic anhydrase XIICAXII
carbonic dehydratase
CA-XII
EC 4.2.1.1
FLJ20151
HsT18816
Tumor antigen HOM-RCC-3.1.3
Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Two transcript variants encoding different isoforms have been identified for this gene.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Breast cancer tissue,FFPE human breast cancer tissue
Species
Human
Lot
D132494
Comments
Comments
***Bio-Techne Response: This review was submitted through the legacy Novus Innovators Program, reflecting a new species or application tested on a primary antibody.***
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