C1qR1/CD93 Antibody [Biotin]

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Biotin
• Concentration: LYOPH

C1qR1/CD93 Antibody [Biotin] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse C1q R1/CD93
  Ala23-Asn572
  Accession # O89103
• Specificity: Detects C1q R1/CD93 in Western blots.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: CD93
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL
• Readout System:
  • Streptavidin Native Protein NBP2-29367
  • Streptavidin Native Protein NBP2-29370
  • Streptavidin Native Protein NBP2-29371

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for C1qR1/CD93 Antibody [Biotin]

• AA4 Antigen
• C1q R1
• C1q receptor 1
• C1q Rp
• C1q/MBL/SPA receptor
• C1qR(P)
• C1qR1
• C1qRp
• CD93 antigenC1qR
• CD93 molecule
• CD93
• CDw93C1QR1
• Collectin Receptor
• Complement component 1 q subcomponent receptor 1
• complement component 1, q subcomponent, receptor 1
• complement component C1q receptor
• dJ737E23.1
• ECSM3
• Ly68
• Matrix-remodeling-associated protein 4
• matrix-remodelling associated 4
• MXRA4

Background

C1q R1, also known as C1q Rp, CD93, Cell Surface Antigen AA4 and lymphocyte antigen 68, is a type I transmembrane protein. It contains a C-type lectin family domain and five EGF-like domains in its extracellular region, as well as a tyrosine kinase-recognition motif in its cytoplasmic region. It is most abundantly expressed on endothelial cells and platelets and is also expressed in neutrophils, glial cells and monocytes. C1q R1 is a marker for early multipotent hematopoietic cells and may participate in C1q/MBL/SPA-mediated enhancement of phagocytic function by monocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for C1qR1/CD93 Antibody (BAF1696)(1)

Publication using BAF1696

• Rona J. Strawbridge, Agneta Hilding, Angela Silveira, Cecilia Österholm, Bengt Sennblad, Olga McLeod et al. Soluble CD93 Is Involved in Metabolic Dysregulation but Does Not Influence Carotid Intima-Media Thickness Diabetes 2016-10-01 [PMID: 27659228]

Bioinformatics

• Gene Symbol: CD93
• Uniprot:
  • O89103()