BTN1A1/Butyrophilin Antibody [Alexa Fluor™ Plus 405]

• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Alexa Fluor Plus 405

BTN1A1/Butyrophilin Antibody [Alexa Fluor™ Plus 405] Summary

• Specificity: Detects mouse BTN1A1/Butyrophilin in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross-reactivity with recombinant human BTN1A1/Butyrophilin is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for BTN1A1/Butyrophilin Antibody [Alexa Fluor™ Plus 405]

• BTBTNbK14H9.2 (butyrophilin, subfamily 1, member A1)
• BTN
• BTN1A1
• butyrophilin subfamily 1 member A1
• butyrophilin, subfamily 1, member A1

Background

Butyrophilin (Greek for “being like butter”; also Btn1a1) is a 66 kDa member of the BTN/MOG family of proteins. It is expressed on secretory mammary epithelium and associates with xanthine dehydrogenase. This is necessary for milk-lipid droplet secretion. Mature mouse Butyrophilin is 498 amino acids (aa) in length. It is a type I transmembrane glycoprotein that contains a 221 aa extracellular domain (ECD) (aa 27‑247) and a 256 aa cytoplasmic region. The ECD contains two V-type Ig‑like domains (aa 29‑141 and aa 149‑235). There are two potential splice variants. One shows a deletion of aa 145‑238, while a second shows a 36 aa substitution for aa 144‑524. Over aa 27‑247, mouse Butyrophilin shares 85% and 67% aa identity with rat and human Butyrophilin, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.