BMP-7 Antibody (M1-F8) - Azide and BSA Free

Western Blot: BMP-7 Antibody (M1-F8) [H00000655-M01] - Analysis of BMP7 expression in transfected 293T cell line by BMP7 monoclonal antibody (M01), clone M1-F8.Lane 1: BMP7 transfected lysate(49.313 KDa).Lane 2: Non-transfected lysate.

Western Blot: BMP-7 Antibody (M1-F8) [H00000655-M01] - BMP7 monoclonal antibody (M01), clone M1-F8. Analysis of BMP7 expression in A-549.

Western Blot: BMP-7 Antibody (M1-F8) [H00000655-M01] - BMP7 monoclonal antibody (M01), clone M1-F8. Analysis of BMP7 expression in Raw 264.7.

Western Blot: BMP-7 Antibody (M1-F8) [H00000655-M01] - BMP7 monoclonal antibody (M01), clone M1-F8. Analysis of BMP7 expression in human uterus myoma.

• Reactivity: Hu, Mu
• Applications: WB, ELISA
• Clone: M1-F8
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

BMP-7 Antibody (M1-F8) - Azide and BSA Free Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: BMP7 (AAH08584, 1 a.a. ~ 431 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MHVRSLRAAAPHSFVALWAPLFLLRSALADFSLDNEVHSSFIHRRLRSQERREMQREILSILGLPHRPRPHLQGKHNSAPMFMLDLYNAMAVEEGGGPGGQGFSYPYKAVFSTQGPPLASLQDSHFLTDADMVMSFVNLVEHDKEFFHPRYHHREFRFDLSKIPEGEAVTAAEFRIYKDYIRERFDNETFRISVYQVLQEHLGRESDLFLLDSRTLWASEEGWLVFDITATSNHWVVNPRHNLGLQLSVETLDGQSINPKLAGLIGRHGPQNKQPFMVAFFKATEVHFRSIRSTGSKQRSQNRSKTPKNQEALRMANVAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGCH
• Localization: Secreted
• Specificity: BMP7 - bone morphogenetic protein 7 (osteogenic protein 1)
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: BMP7
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactivity against cell lysate, tissue lysate, transfected lysate and recombinant protein for WB. It has been used for ELISA.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for BMP-7 Antibody (M1-F8) - Azide and BSA Free

• BMP7
• BMP-7
• bone morphogenetic protein 7
• Eptotermin alfa
• OP-1
• OP-1OP1
• Osteogenic protein 1

Background

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for BMP-7 Antibody (H00000655-M01)(1)

Publication using H00000655-M01

• Loureiro J, Schilte M, Aguilera A et al. BMP-7 blocks mesenchymal conversion of mesothelial cells and prevents peritoneal damage induced by dialysis fluid exposure. Nephrol Dial Transplant;25(4):1098-108. 2010-04-01 [PMID: 20067910]

Bioinformatics

• Gene Symbol: BMP7
• Entrez:
  • 655(Human)
• OMIM:
  • 112267(Human)
• Uniprot:
  • AAH08584(Human)