Human BMP-2 Biologically Active Protein

Images

 
There are currently no images for BMP-2 Protein (NBP2-36435).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Func, PAGE
Concentration
LYOPH

Order Details

Human BMP-2 Biologically Active Protein Summary

Description
A homodimeric protein consisting of two 114 residues glycosylated polypeptide chains and corresponding to amino acids Gln283 - Arg396 of BMP2.

Source: CHO cell line

Preparation
Method
Novus' biologically active proteins are stringently purified to provide only the safest and most highly effective proteins available. This protein was expressed in E. coli, purified by HPLC, QC tested by SDS-PAGE and Western Blot and validated on appropriate cell lines for bioactivity. All HPLC and bioactivity data is provided for your assurance.
Details of Functionality
The ED50, as determined by inducing alkaline phosphatase production using murine ATDC5 cells, is less than 200 ng/ml.
Protein/Peptide Type
Biologically Active Protein
Gene
BMP2
Purity
SDS-PAGE
Endotoxin Note
Less than 1 EU/mg of the rHuBMP-2 as determined by LAL method.

Applications/Dilutions

Theoretical MW
26 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration
LYOPH
Purity
SDS-PAGE
Reconstitution Instructions
Reconstitute with 4 mM HCl to a final concentration of 0.1 mg/ml.

Notes

This lyophilized preparation is stable at 2-8 degrees C, but should be kept at -20 degrees C for long term storage, preferably desiccated. Upon reconstitution, the preparation is most stable at -20 to -80 degrees C, and can be stored for one week at 2-8 degrees C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degrees C to -80 degrees C. Avoid repeated freeze/thaw cycles.

Alternate Names for Human BMP-2 Biologically Active Protein

  • BMP2
  • BMP-2
  • BMP-2A
  • BMP2ABone morphogenetic protein 2A
  • bone morphogenetic protein 2

Background

Bone morphogenetic protein 2 plays a dominant role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. Mature BMP-2 forms disulfide linked homodimers and heterodimers with BMP-7. BMP-2 induces cartilage and bone formation, and BMP-2/BMP-7 heterodimers are even more potent than BMP-2 homodimers. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine production, and is required for cardiac contractility.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 2 years from date of receipt.

Customers Who Viewed This Item Also Viewed...

MAB1419
Species: Hu, Rt
Applications: IHC, CyTOF-ready, ICC, ICFlow
NB110-3638
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, RI
NBP1-89131
Species: Hu
Applications: ICC/IF, IHC, IHC-P
NBP2-42378
Species: Hu
Applications: WB, IHC
NBP1-89134
Species: Hu
Applications: ICC/IF, IHC, IHC-P
NBP2-32263
Species: Hu
Applications: WB, IHC, IP
NB100-56656
Species: Hu, Mu, Rt
Applications: WB
NBP2-45808
Species: Hu
Applications: IHC
AF808
Species: Mu
Applications: WB, IHC, ELISA(Cap), ELISA(Det), Neut, ELISA(Sta)
NBP2-36435
Species: Hu
Applications: Func, PAGE

Publications for BMP-2 Protein (NBP2-36435) (0)

There are no publications for BMP-2 Protein (NBP2-36435).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for BMP-2 Protein (NBP2-36435) (0)

There are no reviews for BMP-2 Protein (NBP2-36435). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

FAQs for BMP-2 Protein (NBP2-36435). (Showing 1 - 1 of 1 FAQ).

  1. I am interested in Bone Morphogenic Protein 2 (BMP-2) for clinical trial in humans. I am using this protein in stem cells culture for future use in humans. Do you have BMP-2 in pharma grade that I can use for humans?
    • Our antibodies are for research purposes only unfortunately. I am sorry we cannot be of further help.

Additional BMP-2 Products

Bioinformatics Tool for BMP-2 Protein (NBP2-36435)

Discover related pathways, diseases and genes to BMP-2 Protein (NBP2-36435). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for BMP-2 Protein (NBP2-36435)

Discover more about diseases related to BMP-2 Protein (NBP2-36435).
 

Pathways for BMP-2 Protein (NBP2-36435)

View related products by pathway.

PTMs for BMP-2 Protein (NBP2-36435)

Learn more about PTMs related to BMP-2 Protein (NBP2-36435).
 

Research Areas for BMP-2 Protein (NBP2-36435)

Find related products by research area.

Blogs on BMP-2

There are no specific blogs for BMP-2, but you can read our latest blog posts.

Customers Who Bought This Also Bought

BMP-2 [Unconjugated]
355-BM-010/CF

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Human BMP-2 Biologically Active Protein and receive a gift card or discount.

Bioinformatics

Gene Symbol BMP2
Entrez