BCL2L10 Antibody

Images

 
Western Blot: BCL2L10 Antibody [NBP1-31681] - A: Raji.
Immunocytochemistry/ Immunofluorescence: BCL2L10 Antibody [NBP1-31681] - Paraformaldehyde-fixed A431, using antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: BCL2L10 Antibody [NBP1-31681] - Paraffin-embedded A549 Xenograft, using antibody at 1:100 dilution.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.32 mg/ml

Order Details

BCL2L10 Antibody Summary

Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human BCL2L10. The exact sequence is proprietary.
Localization
Mitochondrion, Nucleus membrane
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BCL2L10
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0) and 20% Glycerol
Preservative
0.025% Proclin 300
Concentration
1.32 mg/ml
Purity
Immunogen affinity purified

Alternate Names for BCL2L10 Antibody

  • Apoptosis regulator Bcl-B
  • apoptotic protein NrH
  • bcl2-L-10
  • BCL2-like 10 (apoptosis facilitator)
  • bcl-2-like protein 10
  • BCLB
  • BCL-B
  • Boo
  • Diva
  • MGC129810
  • MGC129811

Background

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol BCL2L10
Entrez
Uniprot