Recombinant Human Hrk Western Blot Standard Protein

• Reactivity: Hu
• Applications: WB
• Format: Carrier-Free

Recombinant Human Hrk Western Blot Standard Protein Summary

• Protein/Peptide Type: Recombinant Proteins
• Gene: HRK

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Recombinant Human Hrk Western Blot Standard Protein

• activator of apoptosis harakiri
• activator of apoptosis Hrk
• BCL2-interacting protein
• BH3-interacting domain-containing protein 3
• BID3
• death protein 5
• DP5
• HARAKIRI
• harakiri, BCL2 interacting protein (contains only BH3 domain)
• harakiri, BCL2-interacting protein (contains only BH3 domain)
• Hrk
• Neuronal death protein DP5

Background

HRK (harakiri) is a 10 kDa pro-apoptotic member of the Bcl-2 family of apoptosis regulatory proteins. Hrk lacks significant homology to other Bcl-2 family members except for an 8-amino acid region that is similar to the BH3 domain of Bik (Bcl-2-interacting Killer). Hrk physically interacts with Bcl-2 and Bcl-xL, but not with the pro-apoptotic Bax, BAK, or Bcl-xS. Hrk regulates apoptosis by interacting selectively with survival-promoting Bcl-2 and Bcl-xL to induce cell death.

Bioinformatics

• Gene Symbol: HRK