Recombinant Human Hrk Western Blot Standard Protein

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Format
Carrier-Free

Order Details

Recombinant Human Hrk Western Blot Standard Protein Summary

Protein/Peptide Type
Recombinant Proteins
Gene
HRK

Applications/Dilutions

Dilutions
  • Western Blot

Packaging, Storage & Formulations

Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Recombinant Human Hrk Western Blot Standard Protein

  • activator of apoptosis harakiri
  • activator of apoptosis Hrk
  • BCL2-interacting protein
  • BH3-interacting domain-containing protein 3
  • BID3
  • death protein 5
  • DP5
  • HARAKIRI
  • harakiri, BCL2 interacting protein (contains only BH3 domain)
  • harakiri, BCL2-interacting protein (contains only BH3 domain)
  • Hrk
  • Neuronal death protein DP5

Background

HRK (harakiri) is a 10 kDa pro-apoptotic member of the Bcl-2 family of apoptosis regulatory proteins. Hrk lacks significant homology to other Bcl-2 family members except for an 8-amino acid region that is similar to the BH3 domain of Bik (Bcl-2-interacting Killer). Hrk physically interacts with Bcl-2 and Bcl-xL, but not with the pro-apoptotic Bax, BAK, or Bcl-xS. Hrk regulates apoptosis by interacting selectively with survival-promoting Bcl-2 and Bcl-xL to induce cell death.

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Bioinformatics

Gene Symbol HRK