APRIN Antibody

Western Blot: APRIN Antibody [NBP2-15436] - Sample (30 ug of whole cell lysate) A: Raji 5% SDS PAGE; antibody diluted at 1:1000.

Western Blot: APRIN Antibody [NBP2-15436] - Sample (50 ug of whole cell lysate) A: Mouse brain 5% SDS PAGE; antibody diluted at 1:1000.

• Reactivity: Hu, Mu, Rt, Ch, Xp
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

APRIN Antibody Summary

• Description: Novus Biologicals Rabbit APRIN Antibody (NBP2-15436) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human APRIN. The exact sequence is proprietary.
• Localization: Nucleus
• Predicted Species: Rat (100%), Chicken (100%), Xenopus (98%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PDS5B
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:3000
• Theoretical MW: 165 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Xenopus laevis (98%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS, 1% BSA, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for APRIN Antibody

• Androgen-induced proliferation inhibitorKIAA0979androgen induced inhibitor of proliferation
• Androgen-induced prostate proliferative shutoff-associated protein AS3
• androgen-induced shutoff 3
• AS3APRIN
• CG008
• FLJ23236
• PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
• sister chromatid cohesion protein PDS5 homolog B

Background

This gene encodes a protein that interacts with the conserved protein complex termed cohesion. The cohesion complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: PDS5B
• Uniprot:
  • Q9NTI5(Human)