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Apolipoprotein E R2/ApoE R2 Antibody [DyLight 550]

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Product Details

Summary
Reactivity Hu, Mu, Bv, ChSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 550

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 405
NB100-2217AF405
Alexa Fluor 488
NB100-2217AF488
Alexa Fluor 647
NB100-2217AF647
Alexa Fluor 700
NB100-2217AF700
Biotin
NB100-2217B
DyLight 405
NB100-2217V
DyLight 488
NB100-2217G
DyLight 650
NB100-2217C
FITC
NB100-2217F
HRP
NB100-2217H
Unconjugated
NB100-2217
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Apolipoprotein E R2/ApoE R2 Antibody [DyLight 550] Summary

Immunogen
A synthetic peptide made to a C-terminal portion of the human ApoER2 protein sequence (between residues 800-900). [UniProt# Q14114]
Localization
Type I membrane. Isoforms that contain the exon encoding for a furin-cleavage site are proteolytically processed, leading to a secreted receptor fragment.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
LRP8
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
Application Notes
This ApoER2 antibody is useful in Western blot, where a band is seen at ~106 kDa representing the membrane form of ApoER2. A larger ~130 kDa band may also be seen, representing the glycosylated form of ApoER2.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Apolipoprotein E R2/ApoE R2 Antibody [DyLight 550]

  • ApoER2
  • APOER2HSZ75190
  • Apolipoprotein E R2
  • Apolipoprotein E receptor 2
  • low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
  • low-density lipoprotein receptor-related protein 8
  • Lr8b
  • LRP8
  • LRP-8
  • MCI1

Background

Apolipoprotein E receptor 2 (ApoER2) is an NMDA associated protein found in neurons. It participates in important functions from guiding neurons in the embryonic brain to regulating synaptic signaling. It is also involved in debilitating neurodegenerative diseases such as schizophrenia and Alzheimer's disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Antibody (SA0290)
NBP2-67286
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(CD7D5)
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Apolipoprotein E
R2/ApoE R2 Antibody [ ...
NB100-2217R
Apolipoprotein E R2/ApoE R2 Antibody [DyLight 550]
Species: Hu, Mu, Bv, Ch
Applications: WB, ICC/IF

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Biotin Labeled NB100-2217B
DyLight 488 Labeled NB100-2217G
DyLight 650 Labeled NB100-2217C
HRP Labeled NB100-2217H
Learn about Custom Antibody Labeling

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Bioinformatics

Gene Symbol LRP8
Entrez