Hu, Mu, Ch, BovineApplications:
Species: Hu, Mu, Bv, Ch
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Applications: WB, ELISA, PA
Apolipoprotein E Receptor 2 (ApoER2), also known as LRP8, is a Low-density lipoprotein receptor family member involved in endocytosis and signal transduction. Specifically, ApoER-2 is responsible for the cellular recognition and internalization of ApoE containing lipoproteins, including VLDL and HDL.
ApoER2 is expressed mainly in the brain, placenta, platelets and megakaryocytic cells, but not in the liver. LRP8 mutations can cause myocardial infarction type 1 (MCI1), a condition characterized by the irreversible necrosis of heart muscle secondary to prolonged ischemia. ApoER2 may also play a role in debilitating neurodegenerative diseases such as schizophrenia and Alzheimer's disease.
ApoER2 antibodies are useful tools for studying certian cardiac and neurodegenerative diseases.
PTMs for Apolipoprotein E R2/ApoE R2
Learn more about PTMs related to Apolipoprotein E R2/ApoE R2.PhosphorylationCleavage
Bioinformatics Tool for Apolipoprotein E R2/ApoE R2
Discover related pathways, diseases and genes to Apolipoprotein E R2/ApoE R2. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.