Apolipoprotein E R2/ApoE R2 Products

Antibodies
Apolipoprotein E R2/ApoE R2 A ...
Apolipoprotein E R2/ApoE R2 Antibody
NB100-2217
Species: Hu, Mu, Bv, Ch
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Apolipoprotein E R2/ApoE R2 A ...
Apolipoprotein E R2/ApoE R2 Antibo...
H00007804-M01
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Lysates
Apolipoprotein E R2/ApoE R2 O ...
Apolipoprotein E R2/ApoE R2 Overex...
NBP2-06973
Applications: WB
Proteins
Apolipoprotein E R2/ApoE R2 P ...
Apolipoprotein E R2/ApoE R2 Partia...
H00007804-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
Apolipoprotein E R2/ApoE R2 R ...
Apolipoprotein E R2/ApoE R2 RNAi
H00007804-R06
Species: Hu
Apolipoprotein E R2/ApoE R2 R ...
Apolipoprotein E R2/ApoE R2 RNAi
H00007804-R08
Species: Hu
Apolipoprotein E R2/ApoE R2 R ...
Apolipoprotein E R2/ApoE R2 RNAi
H00007804-R05
Species: Hu

Description

Apolipoprotein E Receptor 2 (ApoER2), also known as LRP8, is a Low-density lipoprotein receptor family member involved in endocytosis and signal transduction. Specifically, ApoER-2 is responsible for the cellular recognition and internalization of ApoE containing lipoproteins, including VLDL and HDL.

ApoER2 is expressed mainly in the brain, placenta, platelets and megakaryocytic cells, but not in the liver. LRP8 mutations can cause myocardial infarction type 1 (MCI1), a condition characterized by the irreversible necrosis of heart muscle secondary to prolonged ischemia. ApoER2 may also play a role in debilitating neurodegenerative diseases such as schizophrenia and Alzheimer's disease.

ApoER2 antibodies are useful tools for studying certian cardiac and neurodegenerative diseases.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 7804
Alternate Names
  • LRP-8
  • low-density lipoprotein receptor-related protein 8
  • Apolipoprotein E receptor 2
  • APOER2HSZ75190
  • MCI1
  • low density lipoprotein receptor-related protein 8, apolipoprotein e receptor

Research Areas for Apolipoprotein E R2/ApoE R2

Find related products by research area and learn more about each of the different research areas below.

Alzheimers Research
Lipid and Metabolism
Neurodegeneration
Neuronal Cell Markers
Neuroscience
Signal Transduction

PTMs for Apolipoprotein E R2/ApoE R2

Learn more about PTMs related to Apolipoprotein E R2/ApoE R2.

Phosphorylation
Cleavage

Bioinformatics Tool for Apolipoprotein E R2/ApoE R2

Discover related pathways, diseases and genes to Apolipoprotein E R2/ApoE R2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.