Aminopeptidase P2/XPNPEP2 Antibody - BSA Free

Analysis in human small intestine and skeletal muscle tissues Corresponding XPNPEP2 RNA-seq data are presented for the same tissues.

Staining of human small intestine shows strong membranous positivity in glandular cells.

Staining of human skeletal muscle shows no positivity in myocytes as expected.

Staining of human lymph node shows no positivity in non-germinal center cells as expected.

Staining of human kidney shows strong membranous positivity in cells in tubules.

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Aminopeptidase P2/XPNPEP2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Aminopeptidase P2/XPNPEP2 Antibody - BSA Free (NBP1-86535) is a polyclonal antibody validated for use in IHC. Anti-Aminopeptidase P2/XPNPEP2 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: VRSQMQKHQKVPTAVLLSALEETAWLFNLRASDIPYNPFFYSYTLLTDSSIRLFANKSRFSSETLSYLNSSCTGPMCVQIEDYSQVRDSIQAYSLGDVRIWIGTSYTMYGI
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: XPNPEP2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  Aminopeptidase P2/XPNPEP2 Protein (NBP1-86535PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Aminopeptidase P2/XPNPEP2 Antibody - BSA Free

• Aminoacylproline aminopeptidase
• Aminopeptidase P2
• APP2
• EC 3.4.11.9
• mAmP
• Membrane-bound aminopeptidase P
• Membrane-bound AmP
• Membrane-bound APP
• xaa-Pro aminopeptidase 2
• XPNPEP2
• X-Pro aminopeptidase 2
• X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound

Background

Aminopeptidase P is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. Structurally, the enzyme is a member of the 'pita bread fold' family and occurs in mammalian tissues in both soluble and GPI-anchored membrane-bound forms. A membrane-bound and soluble form of this enzyme have been identified as products of two separate genes. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Aminopeptidase P2/XPNPEP2 Antibody (NBP1-86535)(1)

Publication using NBP1-86535

• Lindgren D, Bostrom AK, Nilsson K et al. Isolation and characterization of progenitor-like cells from human renal proximal tubules. Am J Pathol 2011-02-01 [PMID: 21281815]

Bioinformatics

• Gene Symbol: XPNPEP2