AHR Antibody [DyLight 488]


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Product Details

Reactivity Hu, Mu, Rt, GPSpecies Glossary
Applications WB, ICC/IF, IP
Please see the vial label for concentration. If unlisted please contact technical services.

AHR Antibody [DyLight 488] Summary

Bacterially expressed human Aryl hydrocarbon Receptor (C-terminus). [UniProt# P35869]
First cytoplasmic, upon binding with ligand and interaction with a HSP90, it translocates to the nucleus
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C in the dark.
DyLight 488
DyLight 488 (A=493, E=518)
50mM Sodium Borate
0.05% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Immunogen affinity purified


Application Notes
This Aryl hydrocarbon Receptor antibody is useful for Immunohistochemistry-paraffin embedded sections, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, ELISA and Western blot. In Western blot a band is seen ~90 to 105 kDa representing AHR (molecular weight varies by species and by strain). In ICC/IF, cytoplasmic staining was observed in MCF-7 cells. In IHC-P, staining was observed in the cytoplasm and nucleus of mouse prostate. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
96 kDa

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 23887904)


Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for AHR Antibody [DyLight 488]

  • Ah receptor
  • AhR
  • AH-receptor
  • aryl hydrocarbon receptor
  • BHLHE76
  • bHLHe76aromatic hydrocarbon receptor
  • Class E basic helix-loop-helix protein 76


The Ah Receptor belongs to a family of proteins comprised of its dimerization partner ARNT (HIF-1 Beta) and the Drosophila proteins PER and SIM. All of these proteins share an N-terminal sequence of ~200 amino acids termed the PAS domain. This receptor, found in a variety of tissues, binds to a specific DNA enhancer sequence and initiates transcription of the mRNA for the cytochrome P-450 (CYPIA1) gene.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for AHR Antibody (NB100-2289G) (0)

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Secondary Antibodies


Isotype Controls

Other Available Formats

Biotin Labeled NB100-2289B
DyLight 550 Labeled NB100-2289R
DyLight 650 Labeled NB100-2289C
HRP Labeled NB100-2289H

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Blogs on AHR.

AHR - A transcription factor regulating immunity and tumorigenesis
The aryl hydrocarbon receptor (AHR) is a ligand activated transcription factor that controls the expression of a diverse set of genes. In the absence of ligand, AHR is retained in the cytoplasm. Upon ligand binding AHR translocates to the nucleus w...  Read full blog post.

Aryl Hydrocarbon Signaling: AIP, AhR, ARNT, BMAL1 and more...
AH receptor-interacting protein (AIP) is a 37 kD immunophilin-like factor found in a variety of tissues with expression levels ranging from high (spleen, thymus, pituitary heart, placenta and skeletal muscle) to low (liver, kidney and lung). It mediat...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol AHR

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