ACOX1 Antibody [DyLight 650]

• Reactivity: Hu
• Applications: ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 650

ACOX1 Antibody [DyLight 650] Summary

• Immunogen: Produced in rabbits immunized with E. coli-derived Human ACOX1 fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ACOX1
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ACOX1 Antibody [DyLight 650]

• ACOXEC 1.3.3.6
• acyl-CoA oxidase 1, palmitoyl
• acyl-CoA oxidase, straight-chain
• acyl-Coenzyme A oxidase 1, palmitoyl
• AOX
• PALMCOX
• Palmitoyl-CoA oxidase
• peroxisomal acyl-coenzyme A oxidase 1
• peroxisomal fatty acyl-CoA oxidase
• SCOXMGC1198
• Straight-chain acyl-CoA oxidase

Background

ACOX1 is encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ACOX1