ACOX1 Antibody (S08-2E5)

Western Blot: ACOX1 Antibody (S08-2E5) [NBP3-19556] - Western blot detection of ACOX1 in Raw264.7, Mouse Liver cell lysates using NBP3-19556 (1:500 diluted). Predicted band size: 74kDa. Observed band size: 74, 48kDa.

Immunocytochemistry/Immunofluorescence: ACOX1 Antibody (S08-2E5) [NBP3-19556] - Immunofluorescence of ACOX1 (green) in hela using NBP3-19556 at dilution 1/50, and DAPI (blue)

• Reactivity: Hu, Mu, Rt
• Applications: WB, ICC/IF
• Clone: S08-2E5
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.3 mg/ml

ACOX1 Antibody (S08-2E5) Summary

• Description: Novus Biologicals Rabbit ACOX1 Antibody (S08-2E5) (NBP3-19556) is a recombinant monoclonal antibody validated for use in WB and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Recombinant protein of mouse ACOX1 (Uniprot # Q9R0H0)
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: ACOX1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1/50
  • Western Blot 1/1000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
• Preservative: 0.01% Sodium Azide
• Concentration: 0.3 mg/ml
• Purity: Affinity purified

Alternate Names for ACOX1 Antibody (S08-2E5)

• ACOXEC 1.3.3.6
• acyl-CoA oxidase 1, palmitoyl
• acyl-CoA oxidase, straight-chain
• acyl-Coenzyme A oxidase 1, palmitoyl
• AOX
• PALMCOX
• Palmitoyl-CoA oxidase
• peroxisomal acyl-coenzyme A oxidase 1
• peroxisomal fatty acyl-CoA oxidase
• SCOXMGC1198
• Straight-chain acyl-CoA oxidase

Background

ACOX1 is encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ACOX1