ABCG8 Antibody [HRP]


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Product Details

Reactivity Hu, MuSpecies Glossary
Applications WB
Please see the vial label for concentration. If unlisted please contact technical services.

ABCG8 Antibody [HRP] Summary

A synthetic peptide from the N-terminal region of human ABCG8 protein. [UniProt# Q9H221]
Integral membrane protein; multi-pass membrane protein
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C in the dark.
No Preservative
Please see the vial label for concentration. If unlisted please contact technical services.
Immunogen affinity purified


  • Western Blot 1:250
Application Notes
This ABCG8 antibody is useful for Immunocytochemistry/Immunofluorescence and Western Blot where a doublet is seen at ~67kDa and ~72kDa. Longer exposure times are needed to visualize the wild type ABCG8. For mouse, 100 ug protein (B6/129AKRFVB liver homogenate) loaded with antibody diluted at 1:500. In ICC/IF puncate membrane localization with some weak nuclear reactivity was observed in HEK293 cells.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
70 kDa
Readout System

Reactivity Notes

Human and mouse.

Alternate Names for ABCG8 Antibody [HRP]

  • ATP-binding cassette sub-family G member 8
  • ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin 2)
  • ATP-binding cassette, sub-family G (WHITE), member 8
  • GBD4ATP-binding cassette, subfamily G, member 8
  • MGC142217
  • sterolin 2
  • sterolin-2
  • STSL


ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. ABCG8, expressed at high levels in the liver and intestine, normally cooperates with ABCG5 to limit intestinal absorption and promote biliary excretion of sterols. The mutated form of this transporter can lead to sterol accumulation and atherosclerosis or sitosterolemia, a rare autosomal recessive disorder, characterized by hyperabsorption of sterols and the inability to excrete sterols into bile.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for ABCG8 Antibody (NB400-117H) (0)

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Secondary Antibodies


Isotype Controls

Other Available Formats

Biotin Labeled NB400-117B
DyLight 488 Labeled NB400-117G
DyLight 550 Labeled NB400-117R
DyLight 650 Labeled NB400-117C

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Research Areas for ABCG8 Antibody (NB400-117H)

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Blogs on ABCG8.

Understanding Sitosterolemia: How ABCG5-ABCG8 Dimer Affects Blood Sterol Levels
The ATP binding cassette (ABC) transporter family is the largest and most diverse family of membrane transport proteins and, as the name suggests, uses the energy generated by ATP hydrolysis to transport substrates across membranes. Eukaryotic ABC tra...  Read full blog post.

ABCG2: A Tumor Protector
ABCG2 is a member of the ATP-binding cassette (ABC) transporter superfamily. Among ABC transporters ABCG2 is particularly interesting for its potential role in protecting cancer stem cells and its complex oligomeric structure (1). The ABC transporters...  Read full blog post.

Exploring how ABCG8 Affects Heart Disease
The high prevalence of atherosclerosis in developed nations is not breaking news; it has been well established that heart disease is the leading cause of death in the United States, and it presents a major socioeconomic burden. Investigators across th...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol ABCG8

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