ABCA7 Antibody (7A1-144) [DyLight 405]


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Product Details

Reactivity MuSpecies Glossary
Applications WB, Flow
This product is unpurified. The exact concentration of antibody is not quantifiable.

ABCA7 Antibody (7A1-144) [DyLight 405] Summary

Mouse ABCA7 stably-transfected HeLa cells. [UniProt# Q91V24]
Cell Membrane and Cytoplasmic
IgG2a Kappa
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Packaging, Storage & Formulations

Store at 4C in the dark.
DyLight 405
DyLight 405 (A=400, E=420)
50mM Sodium Borate
0.05% Sodium Azide
This product is unpurified. The exact concentration of antibody is not quantifiable.


Application Notes
This ABCA7 antibody is useful for Flow Cytometry and Western Blot, where a band is observed at ~240 kDa. This ABCA7 antibody is not reactive in ELISA.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
240 kDa

Reactivity Notes


Alternate Names for ABCA7 Antibody (7A1-144) [DyLight 405]

  • ABCXATP-binding cassette sub-family A member 7
  • ATP-binding cassette, sub-family A (ABC1), member 7
  • Autoantigen SS-N
  • EC
  • EC 3.6.3
  • EC
  • FLJ40025
  • Macrophage ABC transporter


ABCA7 (ATP-binding cassette sub-family A member 7) belongs to "A" subfamily of ABC transporters that predominantly transport lipids and other lipophilic molecules across membranes. ABCA7 shows higher expression in brain, lung, adrenal gland and spleen as well as hematopoietic tissues. It localizes to cell membrane ruffles/phagocytic cups of activated macrophages; to cytoplasm (Golgi and endosomes) of resting macrophages, and to the apical brush border of cells in the proximal tubules of kidney. It is also detected in both the plasma membrane and in intracellular compartments in myelo-lymphatic tissues (peripheral leukocytes, thymus, spleen, and bone marrow). ABCA7 facilitates the transport of phospholipids and, to a lesser extent, cholesterol, across cell membranes to extracellular apoAI and apoE discoidal lipoprotein complexes. Moreover, it implicates in macrophages mediated phagocytosis of apoptotic cells, and binds APOA1 for involving in apolipoprotein-mediated phospholipid efflux from cells. ABCA7 also mediate cholesterol efflux, and can regulate the cellular ceramide homeostasis during keratinocytes differentiation.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies


Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB400-163APC
Biotin Labeled NB400-163B
DyLight 350 Labeled NB400-163UV
DyLight 405LS Labeled NB400-163V3
DyLight 488 Labeled NB400-163G
DyLight 550 Labeled NB400-163R
DyLight 650 Labeled NB400-163C
DyLight 680 Labeled NB400-163FR
DyLight 755 Labeled NB400-163IR
FITC Labeled NB400-163F
HRP Labeled NB400-163H
PE Labeled NB400-163PE
PerCP Labeled NB400-163PCP

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Contact Information

Product PDFs


Gene Symbol ABCA7

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