ABCA7 Antibody (7A1-144) [HRP]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, IHC-P
Clone
7A1-144
Clonality
Monoclonal
Host
Rat
Conjugate
HRP

ABCA7 Antibody (7A1-144) [HRP] Summary

Immunogen
Mouse ABCA7 stably-transfected HeLa cells. [UniProt# Q91V24]
Localization
Cell Membrane and Cytoplasmic
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
ABCA7
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • Immunohistochemistry-Paraffin
Application Notes
This ABCA7 antibody is useful for Flow Cytometry and Western Blot, where a band is observed at ~240 kDa. This ABCA7 antibody is not reactive in ELISA.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
240 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Readout System

Reactivity Notes

Mouse.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Protein G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ABCA7 Antibody (7A1-144) [HRP]

  • ABCA-SSN
  • ABCXATP-binding cassette sub-family A member 7
  • ATP-binding cassette, sub-family A (ABC1), member 7
  • Autoantigen SS-N
  • EC 2.2.1.1
  • EC 3.6.3
  • EC 3.6.3.41
  • FLJ40025
  • Macrophage ABC transporter

Background

ABCA7, an ATP-binding cassette, sub-family A (ABC1), member 7, is highly homologous to ABCA1 and mediates cellular cholesterol and phospholipid release by apolipoproteins. The ABCA7 gene is regulated by sterol in the opposite direction to ABCA1 through SRE/SREBP2. The expression of ABCA7 by this regulation is associated with phagocytic activity. As well, it binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells and may mediate cholesterol efflux.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB400-163APC
Biotin Labeled NB400-163B
DyLight 350 Labeled NB400-163UV
DyLight 405 Labeled NB400-163V
DyLight 488 Labeled NB400-163G
DyLight 550 Labeled NB400-163R
DyLight 650 Labeled NB400-163C
DyLight 680 Labeled NB400-163FR
DyLight 755 Labeled NB400-163IR
FITC Labeled NB400-163F
PE Labeled NB400-163PE
PerCP Labeled NB400-163PCP

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Contact Information

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Bioinformatics

Gene Symbol ABCA7