ABCA7 Products

Antibodies
Proteins
ABCA7 Recombinant Protein Ant ...
ABCA7 Recombinant Protein Antigen
NBP2-14250PEP
Species: Hu
Applications: AC
RNAi
ABCA7 RNAi
ABCA7 RNAi
H00010347-R03
Species: Hu
Applications: RNAi, RNAi SP
ABCA7 RNAi
ABCA7 RNAi
H00010347-R04
Species: Hu
Applications: RNAi, RNAi SP

Description

ATP-binding cassette sub-family A member 7 (ABCA7), is a member of the ATP-binding cassette sub-family A. ABCA7 is thought to have a role in phagocytosis apoptotic cells macrophages.

ABCA-7 is highly homologous to ABCA1, and also mediates cellular cholesterol and phospholipid release by apolipoproteins. The ABCA7 gene is regulated by sterol in the opposite direction to ABCA1 through SRE/SREBP2. The expression of ABCA7 by this regulation is associated with phagocytic activity. As well, it binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. It also may mediate cholesterol efflux.

ABCA7 antibodies are useful for studies of cholesterol formation and lipid processing mechanisms.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Mouse
Product By Gene ID 10347
Alternate Names
  • EC 3.6.3.41
  • ABCA-SSN
  • EC 3.6.3
  • Macrophage ABC transporter
  • EC 2.2.1.1
  • Autoantigen SS-N
  • ABCXATP-binding cassette sub-family A member 7
  • FLJ40025
  • ATP-binding cassette, sub-family A (ABC1), member 7

Research Areas for ABCA7

Find related products by research area and learn more about each of the different research areas below.

ABC Transporters
Astrocyte Markers
Cellular Markers
Cholesterol Metabolism
Glia Markers
Golgi Apparatus Markers
Lipid and Metabolism
Neuroscience
Plasma Membrane Markers
Signal Transduction

PTMs for ABCA7

Learn more about PTMs related to ABCA7.

Phosphorylation
Biotinylation
Cleavage
Glycosylation
Dephosphorylation

Bioinformatics Tool for ABCA7

Discover related pathways, diseases and genes to ABCA7. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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