4-1BB/TNFRSF9/CD137 Antibody Summary
Protein A purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.05% Sodium Azide
Protein A purified
Human. The immunogen shows 63% similarity with CD137 of Mouse.
Alternate Names for 4-1BB/TNFRSF9/CD137 Antibody
- 4-1BB ligand receptor
- CD137 antigen
- ILAhomolog of mouse 4-1BB
- induced by lymphocyte activation (ILA)
- interleukin-activated receptor, homolog of mouse Ly63
- receptor protein 4-1BB
- T cell antigen ILA
- T-cell antigen 4-1BB homolog
- T-cell antigen ILA
- tumor necrosis factor receptor superfamily member 9
- tumor necrosis factor receptor superfamily, member 9
CD137 exists on the cell surface as a monomer with a molecular mass of 30 kDa and as a dimer of 55 kDa. Human and mouse CD137 share 60% amino acid identity. CD137 (4-1BB), a member of the tumour necrosis factor receptor superfamily, is a type I transmembrane glycoprotein expressed on the cell surface of activated splenic T cells and thymocytes. The functions of CD137 in T lymphocytes include regulating activation, proliferation and apoptosis. CD137 and CD28 are costimulatory molecules of T cell activation. Costimulatory molecules are important in initiating anti-tumor immune responses. CD137 plays an important role in regulating T-cell-dependent immune responses. Expression of CD137 correlates negatively with lymphocyte proliferation and positively with the degree of activation-induced cell death caused by mitogen overstimulation. In monocytes, CD137 induces activation, promotes adherence and prolongs survival.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
Customers Who Viewed This Item Also Viewed...
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Applications: WB, ICC/IF, IHC, IHC-P
Species: Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Cell Depl, InhibTFunc
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Applications: WB, Flow, AgAct
Applications: Flow, Func, In vitro, In vivo, Flow-CS
Applications: WB, AgAct
Species: Hu, Mu, Rt, Po, Bv
Applications: WB, ICC/IF
Publications for 4-1BB/TNFRSF9/CD137 Antibody (NBP2-31365) (0)
There are no publications for 4-1BB/TNFRSF9/CD137 Antibody (NBP2-31365).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for 4-1BB/TNFRSF9/CD137 Antibody (NBP2-31365) (0)
There are no reviews for 4-1BB/TNFRSF9/CD137 Antibody (NBP2-31365).
By submitting a review earn points towards our Rewards Program.
- 250 points for product review
- 500 additional points for an image with your product review
- Double points (500) if you are the first to review this product
- Double points (1000) if you are the first to review this product with an image
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
FAQs for 4-1BB/TNFRSF9/CD137 Antibody (NBP2-31365) (0)
Additional 4-1BB/TNFRSF9/CD137 Antibody Products
Related Products by Gene
Bioinformatics Tool for 4-1BB/TNFRSF9/CD137 Antibody (NBP2-31365)
Discover related pathways, diseases and genes to 4-1BB/TNFRSF9/CD137 Antibody (NBP2-31365). Need help?
Read the Bioinformatics Tool Guide
for instructions on using this tool.
Blogs on 4-1BB/TNFRSF9/CD137