OX40/TNFRSF4 Antibody (Ber-ACT35)

Images

 
Immunohistochemistry-Paraffin: OX40/TNFRSF4 Antibody (Ber-ACT35) [NBP2-62202] - Human classic Hodgkin's lymphoma stained with OX40 (clone Ber-ACT35) at dilution 1:50, pH9 heat-induced epitope retrieval. Image from ...read more
Flow Cytometry: OX40/TNFRSF4 Antibody (Ber-ACT35) [NBP2-62202] - Staining of human PMA + ionomycin activated PBMC with anti-human CD134 (Ber-ACT35) PE.
Flow (Cell Surface): OX40/TNFRSF4 Antibody (Ber-ACT35) [NBP2-62202] - Surface staining of human PHA-activated leukocytes with anti-human CD134 (Ber-ACT35) purified, GAM APC.

Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications WB, ELISA, Flow, IHC, IHC-Fr, IHC-P, IP
Clone
Ber-ACT35
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

OX40/TNFRSF4 Antibody (Ber-ACT35) Summary

Immunogen
HTLV 1-transformed HUT-102 cells
Specificity
The mouse monoclonal antibody Ber-ACT35 (also known as ACT35) recognizes an extracellular epitope of OX40/TNFRSF4, an approximately 50 kDa type I transmembrane glycoprotein expressed on activated T cells.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TNFRSF4
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Flow Cytometry 3-6 ug/ml
  • Immunohistochemistry 5-10 ug/ml
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 1:10-1:500
  • Western Blot 1:100-1:2000
Theoretical MW
50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Reviewed Applications
Read 1 Review rated 3
using
NBP2-62202 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
15mM Sodium Azide
Purity
Protein A purified

Alternate Names for OX40/TNFRSF4 Antibody (Ber-ACT35)

  • ACT-135
  • ACT35 antigen
  • ACT35ATC35 antigen
  • CD134 antigen
  • CD134
  • Ly-70
  • OX40 cell surface antigen
  • OX40 homologue
  • OX40
  • OX40L receptor
  • OX40lymphoid activation antigene ACT35
  • TAX transcriptionally-activated glycoprotein 1 receptor
  • tax-transcriptionally activated glycoprotein 1 receptor
  • TNFRSF4
  • tumor necrosis factor receptor superfamily member 4
  • tumor necrosis factor receptor superfamily, member 4
  • Txgp1
  • TXGP1L
  • TXGP1LOX40 antigen

Background

The OX40 receptor is also known as CD134, ACT35, and tumor necrosis factor receptor superfamily member 4. This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX40 receptor binds to the OX40 ligand to provide a co-stimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, imply that these interactions are important in the pathogenesis of some autoimmune diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Review for OX40/TNFRSF4 Antibody (NBP2-62202) (1) 31

Average Rating: 3
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using NBP2-62202:
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Immunofluorescence - paraffin
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Other OX40/TNFRSF4 NBP2-62202
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3
reviewed by:
Christian Schuerch
Immunofluorescence - paraffin Human 03/09/2019
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Summary

ApplicationOther
Sample TestedClassic Hodgkin's lymphoma,Hodgkin lymphoma
SpeciesHuman
LotI don't have it any more

Comments

CommentspH9 heat-induced epitope retrieval

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Secondary Antibodies

 

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Recent Reviews

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Christian Schuerch
03/09/2019
Application: Immunofluorescence - paraffin
Species: Human

Bioinformatics

Gene Symbol TNFRSF4