The mouse monoclonal antibody Ber-ACT35 (also known as ACT35) recognizes an extracellular epitope of OX40/TNFRSF4, an approximately 50 kDa type I transmembrane glycoprotein expressed on activated T cells.
Protein A purified
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50 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read 1 Review rated 3 using NBP2-62202 in the following applications:
tumor necrosis factor receptor superfamily member 4
tumor necrosis factor receptor superfamily, member 4
The OX40 receptor is also known as CD134, ACT35, and tumor necrosis factor receptor superfamily member 4. This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX40 receptor binds to the OX40 ligand to provide a co-stimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, imply that these interactions are important in the pathogenesis of some autoimmune diseases.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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