ZNF143 Antibody (677314) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: ICC/IF
• Clone: 677314
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

ZNF143 Antibody (677314) [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human ZNF143
  Gly459-Asp638
  Accession # P52747
• Specificity: Detects human ZNF143 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) ZNF24, rhZNF206, rhZNF281, rhDC-SCRIPT/ZNF366, rhZNF423, or recombinant mouse Bcl-6 is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ZNF143 Antibody (677314) [Alexa Fluor® 488]

• hStaf
• pHZ-1
• SBF
• SBFzinc finger protein 143 (clone pHZ-1)
• Selenocysteine tRNA gene transcription-activating factor
• SPH-binding factor
• STAF
• STAFpHZ-1
• transcriptional activator Staf
• zinc finger protein 143
• ZNF143

Background

ZNF143 is a 69 kDa (unglycosylated) member of the GLI C2H2-type zinc-finger protein family. Human ZNF143 is 638 amino acids (aa) in length. A second isoform is produced from the deletion of residues 39-69. The protein contains seven C2H2-type zinc fingers, and is expressed in all tissues tested with greatest expression in the ovary. Functionally, ZNF143 serves as a transcriptional activator. Its other functions include acting as an activator for the gene for selenocysteine tRNA (tRNAsec), binding to the SPH motif of small nuclear RNA (snRNA) gene promoters, and participating in efficient U6 RNA polymerase III transcription through its interaction with CHD8. Human ZNF143 shares 97% aa sequence identity with mouse ZNF143.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.