XPD Antibody [Alexa Fluor™ Plus 488]

• Reactivity: Hu, Mu, Rt
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor Plus 488

XPD Antibody [Alexa Fluor™ Plus 488] Summary

• Specificity: Detects human, mouse, and rat XPD in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for XPD Antibody [Alexa Fluor™ Plus 488]

• Basic transcription factor 2 80 kDa subunit
• BTF2 p80
• COFS2
• CXPD
• DNA excision repair protein ERCC-2
• DNA repair protein complementing XP-D cells
• EC 3.6.1
• EC 3.6.4.12
• EM9
• EM9TFIIH basal transcription factor complex 80 kDa subunit
• ERCC2
• excision repair cross-complementing rodent repair deficiency, complementationgroup 2
• MAG
• MGC102762
• MGC126218
• MGC126219
• TFIIH 80 kDa subunit
• TFIIH basal transcription factor complex helicase subunit
• TFIIH basal transcription factor complex helicase XPD subunit
• TTD
• xeroderma pigmentosum complementary group D
• Xeroderma pigmentosum group D-complementing protein
• XPD
• XPDC
• XPDTFIIH p80

Background

The Xeroderma Pigmentosum D (XPD) protein is a DNA helicase that acts as a subunit of the RNA polymerase II complex during nucleotide excision repair (NER) and transcription-coupled repair (TCR). XPD is also involved in p53-mediated apoptosis. XP patients exhibit hypersensitivity to ultraviolet light and have a heightened incidence of skin cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.