CSB Antibody

Images

 
Immunohistochemistry-Paraffin: Rabbit Polyclonal CSB Antibody [NBP1-32405] - CSB antibody [N2C1] detects CSB protein at nucleus on rat hind brain by immunohistochemical analysis.Sample: Paraffin-embedded rat hind brain. ...read more
Immunohistochemistry-Paraffin: Rabbit Polyclonal CSB Antibody [NBP1-32405] - CSB antibody [N2C1] detects CSB protein at nucleus by immunohistochemical analysis. Sample: Paraffin-embedded rat brain.CSB stained by CSB ...read more
Immunoprecipitation: Rabbit Polyclonal CSB Antibody [NBP1-32405] - Immunoprecipitation of CSB protein from 293T whole cell extracts using 5 ug of CSB antibody [N2C1]. Western blot analysis was performed using CSB ...read more
Immunohistochemistry-Paraffin: Rabbit Polyclonal CSB Antibody [NBP1-32405] - CSB antibody [N2C1] detects CSB protein at nucleus by immunohistochemical analysis. Sample: Paraffin-embedded mouse brain. CSB stained by CSB ...read more
Immunocytochemistry/ Immunofluorescence: Rabbit Polyclonal CSB Antibody [NBP1-32405] - CSB antibody [N2C1] detects CSB protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% ...read more
Immunohistochemistry-Paraffin: Rabbit Polyclonal CSB Antibody [NBP1-32405] - CSB antibody [N2C1] detects CSB protein at nucleus on mouse muscle by immunohistochemical analysis. Sample: Paraffin-embedded mouse muscle. ...read more
Western Blot: Rabbit Polyclonal CSB Antibody [NBP1-32405] - Various whole cell extracts (30 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with CSB antibody [N2C1] diluted at 1:1000. The HRP-conjugated ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.69 mg/ml

Order Details

CSB Antibody Summary

Description
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Immunogen
Recombinant protein encompassing a sequence within the center region of human CSB. The exact sequence is proprietary.
Localization
Nucleus
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ERCC6
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Immunoprecipitation 1:100-1:500
  • Western Blot 1:500-1:3000
Theoretical MW
168 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH7), 20% Glycerol
Preservative
0.025% Proclin 300
Concentration
0.69 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CSB Antibody

  • ARMD5
  • ATP-dependent helicase ERCC6
  • CKN2
  • Cockayne syndrome group B protein
  • Cockayne syndrome protein CSB
  • COFS
  • COFS1
  • CSBCockayne syndrome B protein
  • DNA excision repair protein ERCC-6
  • EC 3.6.1
  • EC 3.6.4.-
  • excision repair cross-complementing rodent repair deficiency, complementationgroup 6
  • Rad26 homolog
  • RAD26

Background

This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The protein has ATP-stimulated ATPase activity; there are contradictory publications reporting presence or absence of helicase activity. The protein appears to interact with several transcription and excision repair proteins, and may promote complex formation at repair sites. Mutations in this gene result in Cockayne syndrome type B.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ERCC6