Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Monoclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Goat Polyclonal
Species: Hu, Mu, Rt, Bv, Pm
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
2068 |
| Alternate Names |
- Basic transcription factor 2 80 kDa subunit
- BTF2 p80
- COFS2
- CXPD
- DNA excision repair protein ERCC-2
- DNA repair protein complementing XP-D cells
- EC 3.6.1
- EC 3.6.4.12
- EM9TFIIH basal transcription factor complex 80 kDa subunit
- excision repair cross-complementing rodent repair deficiency, complementationgroup 2
- MAG
- MGC102762
- MGC126218
- MGC126219
- TFIIH 80 kDa subunit
- TFIIH basal transcription factor complex helicase subunit
- TFIIH basal transcription factor complex helicase XPD subunit
- TTD
- xeroderma pigmentosum complementary group D
- Xeroderma pigmentosum group D-complementing protein
- XPDC
- XPDTFIIH p80
|
