Von Willebrand Factor Antibody (IIIE2.34) [Alexa Fluor® 750]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, IHC, IHC-P, ICC/IF
Clone
IIIE2.34
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 750

Order Details

Von Willebrand Factor Antibody (IIIE2.34) [Alexa Fluor® 750] Summary

Immunogen
Recombinant human vWF fragment spanning aa 845-949
Localization
Cytoplasmic
Marker
Endothelial Marker
Specificity
Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
VWF
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Von Willebrand Factor Antibody (IIIE2.34) [Alexa Fluor® 750]

  • coagulation factor VIII VWF
  • F8
  • F8VWF
  • von Willebrand factor
  • VWD
  • vWF

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-48008AF350
Alexa Fluor 405 NBP2-48008AF405
Alexa Fluor 488 NBP2-48008AF488
Alexa Fluor 532 NBP2-48008AF532
Alexa Fluor 594 NBP2-48008AF594
Alexa Fluor 647 NBP2-48008AF647
Alexa Fluor 700 NBP2-48008AF700
Alexa Fluor 750 NBP2-48008AF750
Allophycocyanin NBP2-48008APC
Allophycocyanin/Cy7 NBP2-48008APCCY7
Biotin NBP2-48008B
DyLight 350 NBP2-48008UV
DyLight 405 NBP2-48008V
DyLight 488 NBP2-48008G
DyLight 550 NBP2-48008R
DyLight 594 NBP2-48008DL594
DyLight 650 NBP2-48008C
DyLight 680 NBP2-48008FR
DyLight 755 NBP2-48008IR
FITC NBP2-48008F
HRP NBP2-48008H
Janelia Fluor 549 NBP2-48008JF549
Janelia Fluor 646 NBP2-48008JF646
PE NBP2-48008PE
PE/Atto594 NBP2-48008PEATT594
PE/Cy5.5 NBP2-48008PECY55
PE/Cy7 NBP2-48008PECY7
PerCP NBP2-48008PCP

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Bioinformatics Tool for Von Willebrand Factor Antibody (NBP2-48008AF750)

Discover related pathways, diseases and genes to Von Willebrand Factor Antibody (NBP2-48008AF750). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on Von Willebrand Factor.

Thrombomodulin - A multifunctional protein with roles in inflammation and coagulation
Thrombomodulin, also known as BDCA-3, is a glycosylated transmembrane protein present on the surface of vascular endothelial cells. Thrombomodulin is a high-affinity receptor for thrombin, a key protein in the coagulation cascade. Formation of the...  Read full blog post.

Von Willebrand Factor: An important mediator and carrier of hemostasis
Human Von Willebrand Factor (factor VIII R: Ag) is a 270 kDa multimeric plasma gylcoprotein. Important in the maintenance of hemostasis, it mediates platelet adhesion to injured vessel walls and serves as a carrier and stabilizer for coagulation facto...  Read full blog post.

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Bioinformatics

Gene Symbol VWF