Von Willebrand Factor Antibody (5E7) - BSA Free

Product Discontinued

Von Willebrand Factor Antibody (5E7) - BSA Free Summary

• Immunogen: Factor VIII complex isolated from human plasma adsorbed onto aluminum hydroxide gel
• Epitope: Epitope specificity differs from that of Clone 02
• Marker: Endothelial Cell Marker
• Specificity: Clone 5E7 is specific for human vWf from human serum or plasma
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: VWF
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
• Application Notes: Clone 5E7 reacts strongly with vWf. A strong reaction is seen in ELISA with vWf directly coated onto the microtiterplate, and also when used in sandwich ELISA in combination with a polyclonal antibody against the antigen .

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: 10mM Phosphate (pH 7.4) and 0.5M NaCl
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A or G purified

Alternate Names for Von Willebrand Factor Antibody (5E7) - BSA Free

• coagulation factor VIII VWF
• F8
• F8VWF
• von Willebrand factor
• VWD
• vWF

Background

Von Willebrand factor (vWf) is a series of self-aggregated structures, all derived from common glycoprotein subunits, synthesized in endothelial cells and megakaryocytes. The molecular mass of the monomeric vWf unit is 225 kDa. vWf binds to circulating factor VIIIc (antihemophilic factor), hereby stabilizing the latter thus being an important factor in the normal primary haemostasis

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: VWF