VNN2 Antibody (018) [CoraFluor™ 1]

• Reactivity: Hu
• Applications: ELISA
• Clone: 018
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: CoraFluor 1

VNN2 Antibody (018) [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: This antibody was obtained from a rabbit immunized with purified, recombinant Human VNN2 (Accession#: NP_004656.2; Met 1-Ser 492).
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: VNN2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for VNN2 Antibody (018) [CoraFluor™ 1]

• EC 3.5.1
• EC 3.5.1.92
• FOAP-4
• Glycosylphosphatidyl inositol-anchored protein GPI-80
• GPI-80 variant protein 1
• GPI-80 variant protein 2
• GPI-80 variant protein 3
• GPI-80 variant protein 4
• GPI-80
• pantetheinase
• Protein FOAP-4
• vanin 2
• vanin-2
• Vannin 2
• vascular non-inflammatory molecule 2

Background

VNN2 product is a member of the Vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: VNN2