Human uPAR Quantikine ELISA Kit

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

Human uPAR Quantikine ELISA Kit Summary

Background
The Quantikine Human uPAR Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human uPAR in cell culture supernates, serum, plasma, and urine. It contains NS0-expressed recombinant human uPAR and antibodies raised against the recombinant factor. It has been shown to accurately quantitate the recombinant factor. Results obtained using natural human uPAR showed linear curves that w...ere parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values of natural human uPAR.
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Specificity
Natural and recombinant human uPAR
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
PLAUR

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Interference observed with 1 or more available related molecules.
Publications
Read Publications using DUP00.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human uPAR Quantikine ELISA Kit

  • CD87 antigen
  • CD87
  • Monocyte activation antigen Mo3
  • plasminogen activator, urokinase receptor
  • PLAUR
  • uPAR
  • U-PAR
  • UPARurokinase plasminogen activator surface receptor
  • u-plasminogen activator receptor form 2
  • URKRMO3

Background

The urokinase-type Plasminogen Activator Receptor (uPAR) is a GPI-anchored protein that binds to both the inactive and active forms of uPA. This interaction serves to localize and enhance the proteolytic activity of uPA, leading to increased conversion of Plasminogen to Plasmin. uPA also triggers uPAR-mediated signal transduction, activation of protein tyrosine kinases, gene expression, cell adhesion, and chemotaxis. uPAR can additionally regulate cell adhesion by direct binding to Vitronectin and preventing Integrins from binding to their ligands.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for uPAR (DUP00)(39)

We have publications tested in 1 confirmed species: Human.


Filter By Application
All Applications
Filter By Species
Human
(38)
All Species
Showing Publications 1 - 10 of 39. Show All 39 Publications.
Publications using DUP00 Applications Species
GE Miller, E Chen, E Finegood, D Shimbo, SW Cole Prospective associations between neighborhood violence and monocyte pro-inflammatory transcriptional activity in children Brain, Behavior, and Immunity, 2021;100(0):1-7. 2021 [PMID: 34800620] (Human) Human
S Buhelt, HB Søndergaar, MR Mahler, S Cobanovic, L Börnsen, C Ammitzbøll, AB Oturai, F Sellebjerg Biomarkers of systemic inflammation, soluble IL-2Ralpha and the multiple sclerosis-associated IL2RA SNP rs2104286 in healthy subjects and multiple sclerosis patients Multiple sclerosis and related disorders, 2021;54(0):103140. 2021 [PMID: 34304016] (Human) Human
A Olsson, S Gustavsen, AR Langkilde, TH Hansen, F Sellebjerg, H Bach Sønde, AB Oturai Circulating levels of tight junction proteins in multiple sclerosis: Association with inflammation and disease activity before and after disease modifying therapy Multiple sclerosis and related disorders, 2021;54(0):103136. 2021 [PMID: 34247104] (Human) Human
X Li, D Qi, MY Wang, K Ji, QL Xie, Y Wang, SH Du, HY Fan Salvianolic acid A attenuates steroid resistant nephrotic syndrome through suPAR/uPAR-&alphav&beta3 signaling Inhibition Journal of ethnopharmacology, 2021;279(0):114351. 2021 [PMID: 34157324] (Human) Human
U Jehn, K Schütte-Nü, U Henke, H Pavenstädt, B Suwelack, S Reuter Soluble urokinase-type plasminogen activator receptor (suPAR) is a risk indicator for eGFR loss in kidney transplant recipients Scientific Reports, 2021;11(1):3713. 2021 [PMID: 33580120] (Human) Human
J Wajda, P Dumnicka, W Kolber, M Sporek, B Maziarz, P Ceranowicz, M Ku?niewski, B Ku?nierz-C The Marker of Tubular Injury, Kidney Injury Molecule-1 (KIM-1), in Acute Kidney Injury Complicating Acute Pancreatitis: A Preliminary Study J Clin Med, 2020;9(5):. 2020 [PMID: 32414176] (Human) Human
F Huang, Y Li, R Xu, A Cheng, Y Lv, Q Liu The Plasma Soluble Urokinase Plasminogen Activator Receptor Is Related to Disease Activity of Patients with ANCA-Associated Vasculitis Mediators Inflamm., 2020;2020(0):7850179. 2020 [PMID: 32322165] (Human) Human
JN An, JS Hyeon, Y Jung, YW Choi, JH Kim, SH Yang, S Oh, S Kwon, SH Lee, JH Cho, SH Park, H Ha, DK Kim, JP Lee, GS Hwang Urinary myo-inositol is associated with the clinical outcome in focal segmental glomerulosclerosis Sci Rep, 2019;9(1):14707. 2019 [PMID: 31605028] (Human) Human
W Winnicki, G Sunder-Pla, G Sengölge, A Handisurya, H Herkner, C Kornauth, B Bielesz, L Wagner, Ž Kiki?, S Pajenda, T Reiter, B Schairer, A Schmidt Diagnostic and Prognostic Value of Soluble Urokinase-type Plasminogen Activator Receptor (suPAR) in Focal Segmental Glomerulosclerosis and Impact of Detection Method Sci Rep, 2019;9(1):13783. 2019 [PMID: 31551522] (Human) Human
K Kikuchi, D Saigusa, Y Kanemitsu, Y Matsumoto, P Thanai, N Suzuki, K Mise, H Yamaguchi, T Nakamura, K Asaji, C Mukawa, H Tsukamoto, T Sato, Y Oikawa, T Iwasaki, Y Oe, T Tsukimi, NN Fukuda, HJ Ho, F Nanto-Hara, J Ogura, R Saito, S Nagao, Y Ohsaki, S Shimada, T Suzuki, T Toyohara, E Mishima, H Shima, Y Akiyama, Y Akiyama, M Ichijo, T Matsuhashi, A Matsuo, Y Ogata, CC Yang, C Suzuki, MC Breeggeman, J Heymann, M Shimizu, S Ogawa, N Takahashi, T Suzuki, Y Owada, S Kure, N Mano, T Soga, T Wada, JB Kopp, S Fukuda, A Hozawa, M Yamamoto, S Ito, J Wada, Y Tomioka, T Abe Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease Nat Commun, 2019;10(1):1835. 2019 [PMID: 31015435] (Human) Human
Show All 39 Publications.

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Bioinformatics

Gene Symbol PLAUR