VNN2 Products

Description

VNN2 product is a member of the Vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Bioinformatics

Entrez	8875 Human
Uniprot	NP_004656 Human NP_511043.1 Human
Product By Gene ID	8875
Alternate Names	EC 3.5.1 EC 3.5.1.92 FOAP-4 Glycosylphosphatidyl inositol-anchored protein GPI-80 GPI-80 variant protein 1 GPI-80 variant protein 2 GPI-80 variant protein 3 GPI-80 variant protein 4 GPI-80 pantetheinase Protein FOAP-4 vanin 2 vanin-2 Vanin-2 Vannin 2 vascular non-inflammatory molecule 2