Vav-1 Antibody (591529) [Alexa Fluor® 532]

• Applications: WB
• Clone: 591529
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 532

Vav-1 Antibody (591529) [Alexa Fluor® 532] Summary

• Immunogen: E. coli-derived recombinant human Vav‑1
  Trp25-Leu228
  Accession # P15498
• Specificity: Detects human and mouse Vav‑1 in Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

The Vav-1 proto-oncogene is a guanine nucleotide exchange factor (GEF) for the low molecular weight GTPases of the Rho/Rac family. Vav-1 promotes intracellular signaling by its multiple protein binding motifs. It is a cytosolic protein primarily expressed in hematopoietic cells and plays an essential role in the proliferation and activation of T and B cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.