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Vav-1 Products

Antibodies
Vav-1 Antibody - BSA Free
Vav-1 Antibody - BSA Free
NBP1-86867
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
ELISA Kits
Human Vav-1 ELISA Kit (Colori ...
Human Vav-1 ELISA Kit (Colorimetric)
NBP3-42885
Species: Hu
Applications: ELISA
Lysates
Vav-1 Overexpression Lysate
Vav-1 Overexpression Lysate
NBL1-17701
Species: Hu
Applications: WB
Proteins
Recombinant Human Vav-1 His P ...
Recombinant Human Vav-1 His Protein
NBP2-22938
Species: Hu
Applications: PAGE
Vav-1 Recombinant Protein Ant ...
Vav-1 Recombinant Protein Antigen
NBP1-86867PEP
Species: Hu
Applications: AC

Description

The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 7409
Alternate Names
  • oncogene vav
  • proto-oncogene vav
  • vav 1 guanine nucleotide exchange factor
  • vav proto-oncogene
  • Vav1
  • Vav-1
  • vav-T
  • VAVvav 1 oncogene

Research Areas for Vav-1

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction