USP1 Antibody - BSA Free

Western Blot: USP1 Antibody [NBP2-55036] - Analysis using Anti-USP1 antibody NBP2-55036 (A) shows similar pattern to independent antibody NBP1-85950 (B).

Immunocytochemistry/Immunofluorescence: USP1 Antibody [NBP2-55036] - Staining of human cell line U-251 MG shows localization to nucleoplasm.

• Reactivity: Hu, Rt
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

USP1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit USP1 Antibody - BSA Free (NBP2-55036) is a polyclonal antibody validated for use in IHC, WB and ICC/IF. Anti-USP1 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: HSGITISSGHYTASVKVTDLNSLELDKGNFVVDQMCEIGKPEPLNEEEARGVVENYNDEEVSIRVGGNTQPSKVLNKKNVEAIGLLGGQKSKADYELYN
• Predicted Species: Rat (92%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: USP1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  USP1 Recombinant Protein Antigen (NBP2-55036PEP)

Reactivity Notes

Mouse 89%

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for USP1 Antibody - BSA Free

• Deubiquitinating Enzyme 1
• EC 3.1.2.15
• EC 3.4.19.12
• hUBP
• ubiquitin carboxyl terminal hydrolase 1
• Ubiquitin Carboxyl-Terminal Hydrolase 1
• ubiquitin specific peptidase 1
• ubiquitin specific processing protease 1
• ubiquitin specific protease 1
• Ubiquitin Thioesterase 1
• Ubiquitin thiolesterase 1
• Ubiquitin-specific-processing protease 1
• UBP
• USP1

Background

USP1 encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for USP1 Antibody (NBP2-55036)(1)

Publication using NBP2-55036

• Kim MS, Baek JH, Lee J et al. Deubiquitinase USP1 enhances CCAAT/enhancer-binding protein beta (C/EBP?) stability and accelerates adipogenesis and lipid accumulation Cell death & disease 2023-11-27 [PMID: 38012162] (IHC, Mouse)

Bioinformatics

• Gene Symbol: USP1