UCH-L1/PGP9.5 Antibody (SPM575) [DyLight 680]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Ca, GP, Rb, Sh, ZeSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC-Fr
Clone
SPM575
Clonality
Monoclonal
Host
Mouse

UCH-L1/PGP9.5 Antibody (SPM575) [DyLight 680] Summary

Immunogen
Native UchL1 (PGP9.5) protein from brain
Localization
Cytoplasmic. Endoplasmic Reticulum membrane
Marker
pan-Neuronal Marker
Specificity
This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
UCHL1
Purity
Protein A purified
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Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Conjugate
DyLight 680
Format
DyLight 680 (A=692, E=712)
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA 1-5ug/ml for coating
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Frozen

Alternate Names for UCH-L1/PGP9.5 Antibody (SPM575) [DyLight 680]

  • EC 3.4.19.12
  • EC 6.-
  • Neuron cytoplasmic protein 9.5
  • PARK5
  • PGP 9.5
  • PGP9.5
  • PGP9.5Uch-L1
  • PGP95
  • ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
  • ubiquitin carboxyl-terminal hydrolase isozyme L1
  • ubiquitin C-terminal hydrolase
  • Ubiquitin thioesterase L1
  • UCHL1
  • UCH-L1
  • UCH-L1/PGP9.5

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Diseases for UCH-L1/PGP9.5 Antibody (NBP2-34808FR)

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Research Areas for UCH-L1/PGP9.5 Antibody (NBP2-34808FR)

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Contact Information

Product PDFs

Bioinformatics

Gene Symbol UCHL1
Entrez
Uniprot

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