u-Plasminogen Activator/Urokinase Antibody - BSA Free

Immunohistochemistry-Paraffin: u-Plasminogen Activator/Urokinase Antibody [NBP1-80632] - Staining of human colon shows strong cytoplasmic positivity in goblet cells.

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

u-Plasminogen Activator/Urokinase Antibody - BSA Free Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: YLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGD
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PLAU
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  u-Plasminogen Activator/Urokinase Protein (NBP1-80632PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for u-Plasminogen Activator/Urokinase Antibody - BSA Free

• ATF
• EC 3.4.21
• EC 3.4.21.73
• plasminogen activator, urokinase
• PLAU
• uPA
• u-PA
• uPlasminogen Activator
• u-Plasminogen Activator
• urinary
• Urokinase
• urokinase-type plasminogen activator

Background

Urokinase specifically cleave the zymogen plasminogen to form the active enzyme plasmin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for u-Plasminogen Activator/Urokinase Antibody (NBP1-80632)(3)

Publications using NBP1-80632

• Sohn HS, Choi JW, Jhun J Et al. Tolerogenic nanoparticles induce type II collagen-specific regulatory T cells and ameliorate osteoarthritis Sci Adv 2022-11-25 [PMID: 36427299] (IF/IHC)
  
  Details:
  Citation using the FITC version of this antibody.
• Dinami R, Pompili L, Petti E et al. MiR-182-3p targets TRF2 and impairs tumor growth of triple-negative breast cancer EMBO molecular medicine 2022-11-25 [PMID: 36426578] (Chemotaxis, Human)
• Matsuyama A, Wood GA, Speare R et al. Prognostic significance of the urokinase plasminogen activator system in tissue and serum of dogs with appendicular osteosarcoma PLOS ONE 2022-09-29 [PMID: 36174075] (Immunohistochemistry, Immunocytochemistry/ Immunofluorescence)

Bioinformatics

• Gene Symbol: PLAU
• Entrez:
  • 5328(Human)
• Uniprot:
  • P00749()
  • P00749()
  • P00749()
  • P00749()