TWEAK R/TNFRSF12 Antibody (SN20-07)

Western Blot: TWEAK R/TNFRSF12 Antibody (SN20-07) [NBP2-67729] - Western blot analysis of TWEAK R/TNFRSF12 on C2C12 cell lysates using anti-TWEAK R/TNFRSF12 antibody at 1/500 dilution.

Immunohistochemistry-Paraffin: TWEAK R/TNFRSF12 Antibody (SN20-07) [NBP2-67729] - Analysis of paraffin-embedded mouse uterus tissue using anti-TWEAKR antibody. Counter stained with hematoxylin.

Western Blot: TWEAK R/TNFRSF12 Antibody (SN20-07) [NBP2-67729] - Analysis of TWEAKR on different lysates using anti-TWEAKR antibody at 1/1,000 dilution. Positive control: Lane 1: NIH/3T3 Lane 2: C2C12

Product Discontinued

TWEAK R/TNFRSF12 Antibody (SN20-07) Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Synthetic peptide within Human TWEAK R/TNFRSF12 aa 80-129 / 129. (SwissProt: Q9NP84 Human; SwissProt: Q9CR75 Mouse; Entrez Gene: 302965 Rat)
• Localization: Membrane.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: TNFRSF12A
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Immunoprecipitation
  • Western Blot 1:500-1:1000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: TBS (pH7.4), 0.05% BSA, 40% Glycerol
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for TWEAK R/TNFRSF12 Antibody (SN20-07)

• CD266 antigen
• CD266
• FGF-inducible 14
• Fibroblast growth factor-inducible immediate-early response protein 14
• Fn14
• FN14tumor necrosis factor receptor superfamily member 12A
• TNFRSF12
• TNFRSF12A
• tumor necrosis factor receptor superfamily, member 12A
• TWEAK R
• TWEAKR
• tweak-receptor
• type I transmembrane protein Fn14

Background

TWEAK (otherwise known as TNFRSF12A, Tumor necrosis factor receptor superfamily member 12A), is a member of the TNF family and was first described as a weak inducer of apoptosis in some cell types. It is thought to promote angiogenesis and the proliferation of endothelial cells as well as modulating cellular adhesion to matrix proteins. Recently, a receptor for TWEAK was isolated by expression cloning from a HUVEC cell cDNA library.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TNFRSF12A