Independent Antibodies: Western Blot: TPR Antibody [NB100-2866] - Detection of Human TPR on HeLa whole cell lysate using NB100-2866. TPR was also immunoprecipitated by rabbit anti-TPR antibodies NB100-2864, ...read more
Immunocytochemistry/ Immunofluorescence: TPR Antibody [NB100-2866] - TPR and Mad1 interaction at the Nuclear Pores (green dots). DNA counterstained with DAPI (blue). Image from verified customer review.
Knockdown Validated: TPR Antibody [NB100-2866] - Lane 1 contians wildtype MDA-MB-231 cell lysate nuclear extract. Lanes 2, 3 and 4 contain the TPR knocked down MDA-MB-231 cell lysate nuclear extract. The lowered ...read more
Use in ICC/IF reported in scientific literature (PMID 24344181) and customer review.
267 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read 2 Reviews rated 5 using NB100-2866 in the following applications:
translocated promoter region (to activated MET oncogene)
tumor potentiating region
This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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