TRPM8 Antibody [Biotin]

Images

 
There are currently no images for TRPM8 Antibody (NBP1-97311B).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Biotin

TRPM8 Antibody [Biotin] Summary

Immunogen
A synthetic peptide made to an internal portion of the human TRPM8 protein (between residues 250-300) [UniProt Q7Z2W7]
Localization
Membrane; Multi-pass membrane protein. Ability to translocate to nucleus
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRPM8
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
This TRPM8 antibody is useful for Western Blot where a band is seen ~127 kDa, Immunocytochemistry/Immunofluorescence, and IHC-paraffin embedded sections. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.
Readout System

Reactivity Notes

Human, rat, and mouse.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for TRPM8 Antibody [Biotin]

  • CMR1
  • Long transient receptor potential channel 6
  • LTRPC6
  • LTrpC-6
  • MGC2849
  • short form of the TRPM8 cationic channel
  • transient receptor potential cation channel, subfamily M, member 8
  • Transient receptor potential p8
  • transient receptor potential subfamily M member 8
  • TRPM8
  • TRPP8
  • trp-p8
  • TRPP8transient receptor potential cation channel subfamily M member 8

Background

TRPM8 (TRPP8, LTRPC6) is a transient receptor cation channel that has been shown to be a major cold receptor in sensory neurons. TRPM8 has been theorized to be activated by cold temperatures, voltage, calcium store depletion, some lipids, and also the compounds that produce cooling sensations such as menthol or icilin. TRPM8 is aberrantly over-expressed in pancreatic cancer along with colon, lung, breast and skin cancers, and is proposed to be required for cellular proliferation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-88370
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-31133
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
NB100-1617
Species: Hu, Rt, Pm
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, IP
NB110-40763
Species: Hu, Mu, GP
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P
NB110-74960
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-32096
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, ICC
NBP2-12909
Species: Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP
NBP1-48036
Species: Hu, Ca, Pm
Applications: WB, IHC, IHC-P
NB110-81601
Species: Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-Fr
NB100-98867
Species: Rt
Applications: WB, IHC
AF2747
Species: Mu
Applications: WB, IHC, IP, ELISA(Cap), ELISA(Det), ELISA(Sta)
NB110-74925
Species: Mu
Applications: WB, IHC, IHC-Fr, IHC-P
NB100-810
Species: Mu, Rt
Applications: WB, IHC, IHC-P, PEP-ELISA
NBP1-74138
Species: Hu, Rt
Applications: WB, ICC/IF, IHC
AF4036
Species: Hu
Applications: WB, Simple Western
NB100-98864
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
H00005324-M02
Species: Hu
Applications: WB, ELISA, IHC
NBP1-97311B
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P

Publications for TRPM8 Antibody (NBP1-97311B) (0)

There are no publications for TRPM8 Antibody (NBP1-97311B).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for TRPM8 Antibody (NBP1-97311B) (0)

There are no reviews for TRPM8 Antibody (NBP1-97311B). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for TRPM8 Antibody (NBP1-97311B) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional TRPM8 Products

Bioinformatics Tool for TRPM8 Antibody (NBP1-97311B)

Discover related pathways, diseases and genes to TRPM8 Antibody (NBP1-97311B). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for TRPM8 Antibody (NBP1-97311B)

Discover more about diseases related to TRPM8 Antibody (NBP1-97311B).
 

Pathways for TRPM8 Antibody (NBP1-97311B)

View related products by pathway.

PTMs for TRPM8 Antibody (NBP1-97311B)

Learn more about PTMs related to TRPM8 Antibody (NBP1-97311B).
 

Research Areas for TRPM8 Antibody (NBP1-97311B)

Find related products by research area.

Blogs on TRPM8.

Winter is coming, and TRPM8 welcomes the cold!
TRPM8, or transient receptor potential melastatin 8, is a nonselective cation channel that is activated by cold environments and menthol-like cooling compounds.  While TRPM8 is best known for its location in peripheral nerve endings, it has functio...  Read full blog post.

TRPM8: The Multi-functional Ion Channel
TRPM8 is a transmembrane homo-tetramer ion channel that is activated by cold temperatures, cooling agents, and menthol stimuli. It belongs to a subgroup within the larger family of TRP cation channels (including the TRPV1 capsaicin receptor) that are...  Read full blog post.

Touch Infographic: From Touch Receptors to the Brain
The body contains thousands of receptors and nerves which allow us to experience the sense of touch, also referred to as tactile perception. The somatosensory system allows organisms to perceive and decode a wide range of tactile stimuli to allow for...  Read full blog post.

Customers Who Bought This Also Bought

TRPM8 RNAi
H00079054-R01-20nmol

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our TRPM8 Antibody [Biotin] and receive a gift card or discount.

Bioinformatics

Gene Symbol TRPM8
Entrez