TRPM2 Antibody [Janelia Fluor® 585]

Product Discontinued

TRPM2 Antibody [Janelia Fluor® 585] Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 650 and 700 of human Transient Receptor Potential Cation Channel, Subfamily M, Member 2 using the numbering given in entry NP_003298.1 (GeneID 7226).
• Predicted Species: Mouse (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TRPM2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Rat reactivity reported in (PMID: 21900507).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for TRPM2 Antibody [Janelia Fluor® 585]

• EC 3.6.1.13
• EREG1MGC133383
• Estrogen-responsive element-associated gene 1 protein
• KNP3LTrpC-2
• Long transient receptor potential channel 2
• LTrpC2
• LTRPC2TRPC7transient receptor potential cation channel subfamily M member 2
• NUDT9H
• NUDT9L1
• transient receptor potential cation channel, subfamily M, member 2
• Transient receptor potential channel 7
• TrpC7

Background

TRPM2 belongs to the ion transport protein family. This family contains Sodium, Potassium, Calcium and ion channels. This family has 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. TRPM2 is activated by oxidative stress and confers susceptibility to cell death.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TRPM2