TROP-2 Antibody (MM0588-49D6) [Alexa Fluor® 647]

Flow Cytometry: Mouse Monoclonal TROP-2 Antibody (MM0588-49D6) [Alexa Fluor® 647] [NBP2-11982AF647] - Detection of human TROP-2 on A431 epidermoid carcinoma cells. A431 cells were treated with the TROP-2 AF647 antibody (catalog # NBP2-11982AF647) (BLUE) or mouse IgG2 AF647 isotype control antibody (RED). Image from a verified customer review.

• Reactivity: Hu
• Applications: WB, Flow, CyTOF-ready
• Clone: MM0588-49D6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 647

TROP-2 Antibody (MM0588-49D6) [Alexa Fluor® 647] Summary

• Immunogen: Human recombinant TROP-2
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Mouse
• Gene: TACSTD2
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for TROP-2 Antibody (MM0588-49D6) [Alexa Fluor® 647]

• Cell surface glycoprotein Trop-2
• EGP1
• EGP-1
• epithelial glycoprotein-1
• GA733-1
• GA733-1GP50
• gastrointestinal tumor-associated antigen GA7331
• gp50
• M1S1cell surface glycoprotein TROP2
• Membrane component chromosome 1 surface marker 1
• membrane component, chromosome 1, surface marker 1
• Pancreatic carcinoma marker protein GA733-1
• pancreatic carcinoma marker protein GA7331,40kD glycoprotein, identified by monoclonal GA733
• T16
• TACSTD2
• TROP2
• TROP-2
• TROP2GA7331
• tumor-associated calcium signal transducer 2

Background

TROP2 encodes a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Review for TROP-2 Antibody (NBP2-11982AF647) (1)

Average Rating: 5

(Based on 1 review)

We have 1 review tested in 1 species: Human.

reviewed by: Verified Customer Flow Human 12/10/2023

Summary

• Application: Flow Cytometry
• Sample Tested: A431 human epithelial carcinoma cell line
• Species: Human
• Lot: 2021032202-072121-AF647

Comments

• Comments: A-431 human cancer cell lines were cultured in DMEM + 10% FBS. The cells were detached with accutase and 100,000 cells were stained with TROP-2 AF647-conjugated antibody for 30 minutes. TROP-2 expression was detected in a cytoflex LX.

Bioinformatics

• Gene Symbol: TACSTD2