Species: Hu
Applications: WB, Flow, IHC, CyTOF-ready
Host: Goat Polyclonal
Species: Mu
Applications: WB, Flow, IHC, CyTOF-ready, ICC/IF
Host: Goat Polyclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Applications: Bioactivity
Description
TROP2 encodes a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness. [provided by RefSeq]
Bioinformatics
Entrez |
Human Mouse |
Uniprot |
Human Human Human Human Human Mouse |
Product By Gene ID |
4070 |
Alternate Names |
- Cell surface glycoprotein Trop-2
- EGP1
- EGP-1
- epithelial glycoprotein-1
- GA733-1GP50
- gastrointestinal tumor-associated antigen GA7331
- M1S1cell surface glycoprotein TROP2
- Membrane component chromosome 1 surface marker 1
- membrane component, chromosome 1, surface marker 1
- Pancreatic carcinoma marker protein GA733-1
- pancreatic carcinoma marker protein GA7331,40kD glycoprotein, identified by monoclonal GA733
- TROP2GA7331
- tumor-associated calcium signal transducer 2
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Research Areas for TROP-2
Find related products by research area and learn more about each of the different research areas below.
Signal Transduction