TRMT5 Antibody (OTI1B5) [DyLight 680]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: OTI1B5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 680

TRMT5 Antibody (OTI1B5) [DyLight 680] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-303 of human TRMT5(NP_065861) produced in E.coli.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: TRMT5
• Purity: >95%

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NBP3-44935. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: >95%

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for TRMT5 Antibody (OTI1B5) [DyLight 680]

• KIAA1393EC 2.1.1.31
• M1G-methyltransferase
• TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
• TRM5MGC111453
• tRNA (guanine-N(1)-)-methyltransferase
• tRNA [GM37] methyltransferase
• tRNA methyltransferase 5
• tRNA-N1G37 methyltransferase

Background

tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine (Brule et al., 2004 (PubMed 15248782)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TRMT5